Research on the Development, Implementation Effect and Neural Mechanism of a Physical Intervention Program for College Students With ADHD Based on the Characteristics of Balance Dysfunction
NCT07499427, Not applicable, Terminated, Wuhan Sports University
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Research on the Development, Implementation Effect and Neural Mechanism of a Physical Intervention Program for College Students With ADHD Based on the Characteristics of Balance Dysfunction | ClinicalTrials.gov |
| NCT number | NCT07499427 | ClinicalTrials.gov |
| Status | Terminated | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 130 participants, actual | ClinicalTrials.gov |
| Lead sponsor | Wuhan Sports University | ClinicalTrials.gov |
| Conditions | ADHD - Attention Deficit Disorder With Hyperactivity, ADHD, ADHD - Combined Type, ADHD - Inattentive Type, ADHD Specifically With Executive Function Impairment | ClinicalTrials.gov |
| Interventions | Aerobic Treadmill Training, Progressive Balance Training, Cognitive-Balance Dual-Task Training | ClinicalTrials.gov |
| First posted | 2026-03-30 | ClinicalTrials.gov |
| Last updated | 2026-03-30 | ClinicalTrials.gov |
Registered outcomes 34
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | ADHD Core Symptom Severity | Baseline, Week 4 (mid-intervention), Week 8 (post-intervention) | Change in ADHD core symptoms assessed by the Adult ADHD Self-Report Scale (ASRS). The ASRS is an 18-item self-report questionnaire measuring inattention and hyperactivity-impulsivity symptoms over the past week. Total scores range from 0 to 72, with higher scores indicating greater symptom severity.Score on a scale (0-72) | ClinicalTrials.gov |
| Primary | Working Memory - N-back Task Accuracy | Baseline, Week 4 (mid-intervention), Week 8 (post-intervention) | Change in working memory performance measured by accuracy (%) on the N-back task. Participants respond when the current stimulus matches the one presented N trials earlier. Higher accuracy indicates better working memory.Unit of Measure:Percentage (%) | ClinicalTrials.gov |
| Primary | Prefrontal Cortex Activation | Baseline (pre-intervention), Week 8 (post-intervention) | Change in prefrontal cortex hemodynamic response measured by functional near-infrared spectroscopy (fNIRS) during cognitive tasks (N-back and emotional Stroop). Primary outcomes include oxygenated hemoglobin (HbO) concentration changes in the dorsolateral prefrontal cortex (DLPFC) and orbitofrontal cortex (OFC). | ClinicalTrials.gov |
| Primary | Cognitive Flexibility - Wisconsin Card Sorting Test Perseverative Errors | Baseline, Week 4, Week 8 | Change in cognitive flexibility measured by the number of perseverative errors on the Wisconsin Card Sorting Test (WCST). Perseverative errors occur when participants persist with an incorrect sorting rule despite negative feedback. Fewer perseverative errors indicate better cognitive flexibility.Unit of Measure: Number of errors | ClinicalTrials.gov |
| Primary | Cognitive Flexibility - Wisconsin Card Sorting Test Categories Completed | Baseline, Week 4, Week 8 | Change in cognitive flexibility measured by the number of categories completed on the Wisconsin Card Sorting Test (WCST). A maximum of 6 categories can be completed. More categories completed indicate better cognitive flexibility.Unit of Measure: Number of categories | ClinicalTrials.gov |
| Primary | Inhibitory Control - Stroop Task Interference Effect | Baseline, Week 4, Week 8 | Change in inhibitory control measured by the Stroop interference effect (mean reaction time for incongruent trials minus congruent trials) on the Stroop color-word task. Smaller interference effects indicate better inhibitory control.Unit of Measure: Milliseconds (ms) | ClinicalTrials.gov |
| Primary | Inhibitory Control - Stroop Task Accuracy | Baseline, Week 4, Week 8 | Change in inhibitory control measured by accuracy (%) across all trial types on the Stroop color-word task. Higher accuracy indicates better performance.Unit of Measure:Percentage (%) | ClinicalTrials.gov |
| Primary | Affective Decision-Making - Iowa Gambling Task Net Score | Baseline, Week 4, Week 8 | Change in affective decision-making measured by the net score (total advantageous selections minus total disadvantageous selections) on the modified Iowa Gambling Task. Higher net scores indicate better risk-adjusted decision-making.Unit of Measure:Net score | ClinicalTrials.gov |
| Primary | Affective Decision-Making - Iowa Gambling Task Reaction Time | Baseline, Week 4, Week 8 | Change in affective decision-making measured by mean reaction time (milliseconds) across all trials on the modified Iowa Gambling Task. Shorter reaction times indicate faster decision-making.Unit of Measure: Milliseconds (ms) | ClinicalTrials.gov |
| Primary | Emotional Interference Control - Emotional Stroop Task Interference Effect | Baseline, Week 4, Week 8 | Change in emotional interference control measured by the emotional Stroop interference effect (mean reaction time for negative/emotional words minus neutral words). Larger interference effects indicate greater emotional distractibility.Unit of Measure:Milliseconds (ms) | ClinicalTrials.gov |
| Primary | Emotional Interference Control - Emotional Stroop Task Accuracy | Baseline, Week 4, Week 8 | Change in emotional interference control measured by accuracy (%) across all trial types on the emotional Stroop task. Higher accuracy indicates better performance.Unit of Measure:Percentage (%) | ClinicalTrials.gov |
| Primary | Functional Balance - Berg Balance Scale Total Score | Baseline, Week 4, Week 8 | Change in functional balance measured by the Berg Balance Scale (BBS) total score. The BBS assesses ability to maintain balance during 14 daily activities (e.g., sitting, standing, reaching, turning). Total scores range from 0 to 56. Higher scores indicate better balance performance. | ClinicalTrials.gov |
| Primary | Gait Performance - Functional Gait Assessment Total Score | Baseline, Week 4, Week 8 | Change in complex gait performance measured by the Functional Gait Assessment (FGA) total score. The FGA evaluates gait during 10 tasks (e.g., walking with head turns, stepping over obstacles, walking backward). Total scores range from 0 to 30. Higher scores indicate better gait performance. | ClinicalTrials.gov |
| Primary | Dynamic Balance - Y-Balance Test Right Anterior Reach Distance | Baseline, Week 4, Week 8 | Change in dynamic balance measured by the normalized reach distance (%) of the right leg in the anterior direction on the Y-Balance Test. Reach distance is normalized to leg length. Longer reach distances indicate better dynamic balance. | ClinicalTrials.gov |
| Primary | Dynamic Balance - Y-Balance Test Right Posteromedial Reach Distance | Baseline, Week 4, Week 8 | Change in dynamic balance measured by the normalized reach distance (%) of the right leg in the posteromedial direction on the Y-Balance Test. Reach distance is normalized to leg length. Longer reach distances indicate better dynamic balance. | ClinicalTrials.gov |
| Primary | Dynamic Balance - Y-Balance Test Right Posterolateral Reach Distance | Baseline, Week 4, Week 8 | Change in dynamic balance measured by the normalized reach distance (%) of the right leg in the posterolateral direction on the Y-Balance Test. Reach distance is normalized to leg length. Longer reach distances indicate better dynamic balance. | ClinicalTrials.gov |
| Primary | Dynamic Balance - Y-Balance Test Left Anterior Reach Distance | Baseline, Week 4, Week 8 | Change in dynamic balance measured by the normalized reach distance (%) of the left leg in the anterior direction on the Y-Balance Test. Reach distance is normalized to leg length. Longer reach distances indicate better dynamic balance. | ClinicalTrials.gov |
| Primary | Dynamic Balance - Y-Balance Test Left Posteromedial Reach Distance | Baseline, Week 4, Week 8 | Change in dynamic balance measured by the normalized reach distance (%) of the left leg in the posteromedial direction on the Y-Balance Test. Reach distance is normalized to leg length. Longer reach distances indicate better dynamic balance. | ClinicalTrials.gov |
| Primary | Dynamic Balance - Y-Balance Test Left Posterolateral Reach Distance | Baseline, Week 4, Week 8 | Change in dynamic balance measured by the normalized reach distance (%) of the left leg in the posterolateral direction on the Y-Balance Test. Reach distance is normalized to leg length. Longer reach distances indicate better dynamic balance. | ClinicalTrials.gov |
| Primary | Limb Asymmetry - Y-Balance Test Anterior Asymmetry Index | Baseline, Week 4, Week 8 | Change in inter-limb coordination measured by the anterior asymmetry index (%) on the Y-Balance Test. The index is calculated as the absolute difference between right and left anterior reach distances divided by the average of both legs. Lower asymmetry indicates better bilateral coordination. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 2
The papers the trial lists on ClinicalTrials.gov.
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 6
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| 1-Back Task | Primary outcome | ConductCognition |
| 2-Back Task | Primary outcome | ConductCognition |
| Card Sorting Test (Berg) | Primary outcome | ConductCognition |
| Emotional Stroop Task | Primary outcome | ConductCognition |
| Iowa Gambling Lite | Primary outcome | ConductCognition |
| Stroop Color-Word Test | Primary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)