Trial · NCT07508488
Registered outcomes28
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
1 to 20 of 28
Download this page as JSON| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Changes in IFNγ in CA scalp | Baseline to Week 24 | Changes in TH1 markers in Cicatricial Alopecias on the scalp from Baseline to Week 24 |
| Primary | Changes in CCL5 in CA scalp | Baseline to Week 24 | Changes in TH1 markers in Cicatricial Alopecias on the scalp from Baseline to Week 24 |
| Primary | Changes in CXCL9 in CA scalp | Baseline to Week 24 | Changes in TH1 markers in Cicatricial Alopecias on the scalp from Baseline to Week 24 |
| Primary | Changes in CXCL10 in CA scalp | Baseline to Week 24 | Changes in TH1 markers in Cicatricial Alopecias on the scalp from Baseline to Week 24 |
| Primary | Changes in TGFB1/2 in CA scalp | Baseline to Week 24 | Changes in biomarkers of fibrosis in Cicatricial Alopecias on the scalp from Baseline to Week 24 |
| Primary | Changes in vimentin in CA scalp | Baseline to Week 24 | Changes in biomarkers of fibrosis in Cicatricial Alopecias on the scalp from Baseline to Week 24 |
| Primary | Changes in fibronectin CA scalp | Baseline to Week 24 | Changes in biomarkers of fibrosis in Cicatricial Alopecias on the scalp from Baseline to Week 24 |
| Primary | Changes in CTGF in CA scalp | Baseline to Week 24 | Changes in biomarkers of fibrosis in Cicatricial Alopecias on the scalp from Baseline to Week 24 |
| Secondary | Changes in IFNγ in CA scalp | Week 24 to Week 48 | Changes in TH1 markers in Cicatricial Alopecias on the scalp from Baseline to Week 24 |
| Secondary | Changes in CCL5 in CA scalp | Week 24 to Week 48 | Changes in TH1 markers in Cicatricial Alopecias on the scalp from Baseline to Week 24 |
| Secondary | Changes in CXCL9 in CA scalp | Week 24 to Week 48 | Changes in TH1 markers in Cicatricial Alopecias on the scalp from Baseline to Week 24 |
| Secondary | Changes in CXCL10 in CA scalp | Week 24 to Week 48 | Changes in TH1 markers in Cicatricial Alopecias on the scalp from Baseline to Week 24 |
| Secondary | Changes in TGFB1/2 in CA scalp | Week 24 to Week 48 | Changes in biomarkers of fibrosis in Cicatricial Alopecias on the scalp from Baseline to Week 24 |
| Secondary | Changes in vimentin in CA scalp | Week 24 to Week 48 | Changes in biomarkers of fibrosis in Cicatricial Alopecias on the scalp from Baseline to Week 24 |
| Secondary | Changes in fibronectin CA scalp | Week 24 to Week 48 | Changes in biomarkers of fibrosis in Cicatricial Alopecias on the scalp from Baseline to Week 24 |
| Secondary | Changes in CTGF in CA scalp | Week 24 to Week 48 | Changes in biomarkers of fibrosis in Cicatricial Alopecias on the scalp from Baseline to Week 24 |
| Secondary | Change in The Central Hair Loss Grade (CHLG) | Baseline to Week 24; Baseline to Week 48 | Change in CHLG from baseline at week 24 and week 48. The Central Hair Loss Grade is a clinical measure of severity that uses a 6 points scale (0 no central scalp hair loss, 1 - minimal central scalp hair loss, 2 - clinically evident central scalp hair loss, 3-5 advanced central scalp hair loss). |
| Secondary | Change in Frontal Fibrosing Alopecia Severity Index (FFASI) | Baseline to Week 24; Baseline to Week 48 | Change in FFASI from baseline at week 24 and week 48. The Frontal Fibrosis Alopecia Severity Index utilizes clinical images of the entire hairline divided into 4 sections. Score from 1-5, with higher score indicating more severity. |
| Secondary | Changes in mRNA Levels of CCL5 gene expression in skin biopsies | baseline and week 24 | Evaluation of how the two skin conditions (CCCA and FFA) present themselves at the microscopic level. The skin samples will be obtained via biopsies. Changes in mRNA Levels of CCL5 gene expression in skin biopsies quantified by normalized Ct values obtained by quantitative real-time PCR assay, measured at baseline and week 24. The unit of the outcome is called Ct value and it represents the number of amplification cycles to reach a level of fluorescence in the experiment. The Ct value is directly associated to the level of expression of a gene |
| Secondary | Change in Alopecia Areata Quality of Life Index (AA-QLI) | Week 24 and Week 48 | Change in Alopecia Areata Quality of Life Index (AA-QLI) in week 24 and week 48. The scores range from 0 - 30 with 0 representing no impact to quality of life and 30 representing extremely large impact. |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/trials/v1/NCT07508488/registered