Trial · NCT07511400
The Role of NaV1.8 in Human Pain Models
NCT07511400, Early phase 1, Completed, Medical University of Vienna
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. The Role of NaV1.8 in Human Pain Models. Trials, record NCT07511400. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07511400
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- The Role of NaV1.8 in Human Pain Models
- NCT number
- NCT07511400
- Status
- Completed
- Phases
- Early phase 1
- Enrollment
- 67 participants, actual
- Lead sponsor
- Medical University of Vienna
- Conditions
- Pain, Acute Pain, Healthy Volunteer Study
- Interventions
- Suzetrigine, Lidocaine (drug), Control Solution
- First posted
- 2026-04-06
- Last updated
- 2026-06-24
Source ClinicalTrials.gov
Registered outcomes6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Pain Intensity: Electrical stimulation | 1.5 minutes post-injection. | Metric: Numerical Rating Scale (0-100; 0=No pain, 100=Worst imaginable pain). Calculation: The average of all provided pain ratings divided by the number of delivered stimuli (maximum of 23 stimuli). If a subject stops the test upon reaching a rating of 30, the average is calculated based on the actual number of stimuli delivered. |
| Primary | Geometric Mean Pain Intensity: Mechanical stimulation | 1.5 minutes post-injection. | Metric: Numerical Rating Scale (0-100; 0=No pain, 100=Worst imaginable pain). Calculation: The geometric mean of the pain ratings recorded from three standardized mechanical stimuli (3.6N force). |
| Primary | Area Under the Curve (AUC): Capsaicin injection | From injection until 0 pain for 30 seconds. | Metric: Numerical Rating Scale (0-100; 0=No pain, 100=Worst imaginable pain). Calculation: The AUC of pain ratings provided every 5 seconds, starting from the time of injection until a consecutive rating of 0 is maintained for 30 seconds. |
| Primary | Area Under the Curve (AUC): Acid injection | 110 seconds | Metric: Numerical Rating Scale (0-100; 0=No pain, 100=Worst imaginable pain). Calculation: The AUC of pain ratings provided every 5 seconds during the pH decrease from 7.2 to 5.4. |
| Primary | Area Under the Curve (AUC): Heat injection | 150 seconds | Metric: Numerical Rating Scale (0-100; 0=No pain, 100=Worst imaginable pain). Calculation: The AUC of pain ratings provided every 5 seconds during the temperature increase from 23°C to 52°C. |
| Primary | Area Under the Curve (AUC): Cold injection | 150 seconds | Metric: Numerical Rating Scale (0-100; 0=No pain, 100=Worst imaginable pain). Calculation: The AUC of pain ratings provided every 5 seconds during the temperature decrease from 23°C to 4°C. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07511400
GET https://conductscience.org/api/trials/v1/NCT07511400/registered