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Trial · NCT07524101

Registered outcomes27

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryMajor adverse cardiovascular events3 yearsComposite of cardiovascular death, myocardial infarction, stroke, hospitalization for unstable angina, or coronary revascularization.
SecondaryCKD progression3 yearsCKD progression: ≥40% decline in eGFR from baseline, confirmed on at least two consecutive measurements during follow-up.
SecondaryCardiovascular death.3 yearsDeath due to cardiovascular causes during follow-up.
SecondaryMyocardial infarction.3 yearsOccurrence of myocardial infarction during follow-up.
SecondaryStroke.3 yearsOccurrence of stroke during follow-up
SecondaryHospitalization for unstable angina.3 yearsHospitalization due to unstable angina during follow-up.
SecondaryCoronary revascularization.3 yearsAny coronary revascularization procedure, including percutaneous coronary intervention or coronary artery bypass graft surgery, during follow-up.
SecondaryComposite of cardiovascular death, myocardial infarction, and stroke.3 yearsFirst occurrence of cardiovascular death, myocardial infarction, or stroke during follow-up.
SecondaryComposite of cardiovascular death, myocardial infarction, stroke, and hospitalization for unstable angina3 yearsFirst occurrence of cardiovascular death, myocardial infarction, stroke, or hospitalization for unstable angina during follow-up
SecondaryComposite of cardiovascular death, myocardial infarction, stroke, and coronary revascularization.3 yearsFirst occurrence of cardiovascular death, myocardial infarction, stroke, or coronary revascularization during follow-up.
SecondaryComposite of all-cause death, myocardial infarction, stroke, hospitalization for unstable angina, and coronary revascularization.3 yearsFirst occurrence of all-cause death, myocardial infarction, stroke, hospitalization for unstable angina, or coronary revascularization during follow-up.
SecondaryProportion of participants achieving the LDL-C <70 mg/dL in each group.3 yearsProportion of participants achieving a low-density lipoprotein cholesterol (LDL-C) level below 70 mg/dL in each treatment group during follow-up.
SecondaryProportion of participants achieving LDL-C <55 mg/dL in each group.3 yearsProportion of participants achieving a low-density lipoprotein cholesterol (LDL-C) level below 55 mg/dL in each treatment group during follow-up.
SecondaryProportion of participants crossing over to the non-assigned treatment group in each group.3 yearsProportion of participants who crossed over from the assigned treatment group to the non-assigned treatment group during follow-up.
SecondaryNew-onset diabetes mellitus.3 yearsOccurrence of new-onset diabetes mellitus during follow-up.
SecondaryNew-onset diabetes mellitus requiring initiation of antidiabetic medication.3 yearsOccurrence of new-onset diabetes mellitus requiring initiation of antidiabetic medication during follow-up.
SecondaryWorsening glycemic control.3 yearsOccurrence of worsening glycemic control during follow-up
SecondaryMarked decline in kidney function3 yearseGFR \<10 mL/min/1.73 m², confirmed on at least two consecutive measurements during follow-up.
SecondaryInitiation of dialysis or kidney transplantation.3 yearsInitiation of maintenance dialysis or receipt of kidney transplantation during follow-up.
SecondaryStatin-associated muscle symptoms requiring a change in regimen or dose.3 yearsOccurrence of statin-associated muscle symptoms requiring a change in statin regimen or dose during follow-up.

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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