Trial · NCT07526558
Mast Cell Treatment in Post-tick Bite Illness (PTBI)
NCT07526558, Phase 2, Not yet recruiting, University of North Carolina, Chapel Hill
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Mast Cell Treatment in Post-tick Bite Illness (PTBI). Trials, record NCT07526558. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07526558
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Mast Cell Treatment in Post-tick Bite Illness (PTBI)
- NCT number
- NCT07526558
- Status
- Not yet recruiting
- Phases
- Phase 2
- Enrollment
- 50 participants, estimated
- Lead sponsor
- University of North Carolina, Chapel Hill
- Conditions
- Tick Bites, Mast Cell Activation Disorders, Tick-Borne Diseases
- Interventions
- Ketotifen, fexofenadine, Cromolyn Sodium
- First posted
- 2026-04-13
- Last updated
- 2026-11-09
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in Mast Cell Activation Symptom Score | Baseline, after 4 months of intervention | Symptoms will be assessed using the mast cell activity symptom scale, which is based on the American Academy of Allergy, Asthma and Immunology scale but with modifications to include neuro/psych symptoms. The construct is a Likert metric with participants ranking symptoms based on categories of frequency, severity and impact to daily life ("bothersome"). Each item is rated on a 4-point scale from 1 ("not at all") to 4 ("extremely") resulting in a range of 63 - 252. Higher scores are correlated with worse symptoms. |
| Secondary | Change in General Symptoms Questionnaire-30 (GSQ-30) Total Score | Baseline, after 4 months of intervention | The General Symptoms Questionnaire-30 (GSQ-30) is a 30-item patient-reported outcome measure designed to assess multi-system symptom burden. Each item is rated on a 5-point Likert scale from 0 ("not at all") to 4 ("very much"), resulting in a total score ranging from 0 to 120. Higher scores indicate greater symptom burden. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07526558
GET https://conductscience.org/api/trials/v1/NCT07526558/registered