Trial · NCT07537166
0.01% and 0.025% Atropine Eye Drops Combined Auricular Acupoint Stimulation on Myopia Control and Corneal Endothelium Change
NCT07537166, Not applicable, Enrolling by invitation, China Medical University Hospital
3 sourcestrials-2026-11-12-0.4.0
Cite this record
ConductScience Library. 0.01% and 0.025% Atropine Eye Drops Combined Auricular Acupoint Stimulation on Myopia Control and Corneal Endothelium Change. Trials, record NCT07537166. Release trials-2026-11-12-0.4.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07537166
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- 0.01% and 0.025% Atropine Eye Drops Combined Auricular Acupoint Stimulation on Myopia Control and Corneal Endothelium Change
- NCT number
- NCT07537166
- Status
- Enrolling by invitation
- Phases
- Not applicable
- Enrollment
- 420 participants, estimated
- Lead sponsor
- China Medical University Hospital
- Conditions
- Acupressure
- Interventions
- Auricular acupoint stimulation, 0.01% concentration atropine drops, 0.025% atropine eye drops, Artificial Tears (AT)
- First posted
- 2026-04-17
- Last updated
- 2026-06-04
Source ClinicalTrials.gov
Registered outcomes10
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in corneal curvature (Keratometry) | Baseline to 3 months once per week. | Mean corneal curvature will be measured using an autorefractor keratometer. The average keratometric value (K) will be recorded. Unit of Measure: Diopters (D) |
| Primary | Change in refractive error (Spherical Equivalent) | Baseline to 3 months once per week. | Spherical equivalent will be calculated as sphere + 1/2 cylinder based on cycloplegic refraction. Unit of Measure: Diopters (D) |
| Primary | Change in amplitude of accommodation | Baseline to 3 months once per week. | Amplitude of accommodation will be assessed using the push-up method. Unit of Measure: Diopters (D) |
| Primary | Change in axial length | Baseline to 3 months once per week. | Axial length will be measured using optical biometry. Unit of Measure: Millimeters (mm) |
| Primary | Change in anterior chamber depth | Baseline to 3 months once per week. | Anterior chamber depth will be measured using optical biometry. Unit of Measure: Millimeters (mm) |
| Primary | Change in intraocular pressure | Baseline to 3 months once per week. | Intraocular pressure will be measured using non-contact tonometry. Unit of Measure: mmHg |
| Primary | Change in corneal topographic parameters | Baseline to 3 months once per week. | Corneal topography will be used to assess corneal surface characteristics, including corneal astigmatism and curvature distribution. Unit of Measure: Diopters (D) |
| Primary | Change in retinal structure assessed by optical coherence tomography | Baseline to 3 months once per week. | Retinal thickness and macular structure will be evaluated using OCT. Unit of Measure: Micrometers (μm) |
| Primary | Change in central corneal thickness | Baseline to 3 months once per week. | Central corneal thickness will be measured using pachymetry. Unit of Measure: Micrometers (μm) |
| Other | Safety monitoring index: Corneal endothelial cell parameters | Baseline to 3 months once per week. | The following quantitative parameters will be recorded: endothelial cell density (ECD), coefficient of variation in cell size (CV), percentage of hexagonal cells (HEX), and average cell area. These are imaging-derived quantitative measurements rather than a scored scale; therefore, no minimum or maximum scale values apply. Normal range: ECD: 3,100-5,000 cells/mm² CV: 18-40% Percentage of HEX: 50-70% Average cell area: 230-680 μm² Higher ECD and hexagonality generally indicate better corneal endothelial status, whereas lower CV and average cell area indicate more stable endothelial morphology. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Source
- Release
- trials-2026-11-12-0.4.0
- Release manifest SHA-256
- 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4
- Registry capture
- 2026-11-12
- Results copy, AACT
- 2026-03-23
- NIH clinical studies file
- 2026-11-13
Source ClinicalTrials.gov
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNone stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07537166
GET https://conductscience.org/api/trials/v1/NCT07537166/registered