Trial · NCT07537816
Effects of Vadadustat on Anemia, Quality of Life, and Inflammation in Dialysis Patients
NCT07537816, Phase 4, Not yet recruiting, Mackay Memorial Hospital
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Effects of Vadadustat on Anemia, Quality of Life, and Inflammation in Dialysis Patients. Trials, record NCT07537816. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07537816
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Effects of Vadadustat on Anemia, Quality of Life, and Inflammation in Dialysis Patients
- NCT number
- NCT07537816
- Status
- Not yet recruiting
- Phases
- Phase 4
- Enrollment
- 40 participants, estimated
- Lead sponsor
- Mackay Memorial Hospital
- Conditions
- Renal Anemia
- Interventions
- Vadadustat
- First posted
- 2026-04-17
- Last updated
- 2026-04-23
Source ClinicalTrials.gov
Registered outcomes10
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in Hemoglobin | Baseline and end of each 8-week treatment period (up to 5 months). | Within-participant change in hemoglobin during add-on vadadustat treatment compared with background darbepoetin alfa alone in this two-period, two-sequence crossover study in patients receiving maintenance peritoneal dialysis. |
| Secondary | Change in SF-36 Physical Component Summary score | Baseline and end of each 8-week treatment period (up to 5 months). | Change in health-related quality of life as assessed by the 36-Item Short Form Health Survey (SF-36) Physical Component Summary (PCS) score during add-on vadadustat treatment compared with background darbepoetin alfa alone in this two-period, two-sequence crossover study in patients receiving maintenance peritoneal dialysis. Higher scores indicate better physical health status. |
| Secondary | Change in SF-36 Mental Component Summary score | Baseline and end of each 8-week treatment period (up to 5 months). | Change in health-related quality of life as assessed by the 36-Item Short Form Health Survey (SF-36) Mental Component Summary (MCS) score during add-on vadadustat treatment compared with background darbepoetin alfa alone in this two-period, two-sequence crossover study in patients receiving maintenance peritoneal dialysis. Higher scores indicate better mental health status. |
| Secondary | Change in C-reactive protein | Baseline and monthly during the study period, up to 5 months. | Change in serum C-reactive protein during add-on vadadustat treatment compared with background darbepoetin alfa alone. |
| Secondary | Change in erythrocyte sedimentation rate | Baseline and monthly during the study period, up to 5 months. | Change in erythrocyte sedimentation rate during add-on vadadustat treatment compared with background darbepoetin alfa alone. |
| Secondary | Change in interleukin-6 | Baseline and monthly during the study period, up to 5 months. | Change in serum interleukin-6 during add-on vadadustat treatment compared with background darbepoetin alfa alone. |
| Secondary | Change in serum iron | Baseline and monthly during the study period, up to 5 months. | Change in serum iron during add-on vadadustat treatment compared with background darbepoetin alfa alone. |
| Secondary | Change in total iron-binding capacity | Baseline and monthly during the study period, up to 5 months. | Change in serum total iron-binding capacity during add-on vadadustat treatment compared with background darbepoetin alfa alone. |
| Secondary | Change in ferritin | Baseline and monthly during the study period, up to 5 months. | Change in serum ferritin during add-on vadadustat treatment compared with background darbepoetin alfa alone. |
| Secondary | Change in transferrin saturation | Baseline and monthly during the study period, up to 5 months. | Change in transferrin saturation during add-on vadadustat treatment compared with background darbepoetin alfa alone. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07537816
GET https://conductscience.org/api/trials/v1/NCT07537816/registered