Trial · NCT07553143
Effect of Preoperative Melatonin on Quality of Recovery After Elective Laparoscopic Cholecystectomy
NCT07553143, Not applicable, Recruiting, Armed Forces Medical Institute Bangladesh
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Effect of Preoperative Melatonin on Quality of Recovery After Elective Laparoscopic Cholecystectomy. Trials, record NCT07553143. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07553143
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Effect of Preoperative Melatonin on Quality of Recovery After Elective Laparoscopic Cholecystectomy
- NCT number
- NCT07553143
- Status
- Recruiting
- Phases
- Not applicable
- Enrollment
- 84 participants, estimated
- Lead sponsor
- Armed Forces Medical Institute Bangladesh
- Conditions
- Laparoscopic Cholecystectomy, Postoperative Quality of Recovery, Preoperative Anxiety, Postoperative Sleep Quality, Opioid Consumption, Postoperative, PONV in Laparoscopic Cholocystectomies
- Interventions
- Melatonin (N-acetyl-5-methoxytryptamine), Placebo
- First posted
- 2026-04-27
- Last updated
- 2026-09-30
Source ClinicalTrials.gov
Registered outcomes6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Quality of Recovery-15 (QoR-15) total score | 24 ± 2 hours after surgery | Validated 15-item patient-reported outcome. Range 0-150; higher = better recovery. MCID = 6.0 points. |
| Secondary | Sleep quality | Morning after surgery (approximately 16-24 hours post-op) | Measured using the Richards-Campbell Sleep Questionnaire (RCSQ), a 5-item visual analogue scale assessing depth, latency, awakenings, return to sleep, and overall quality of sleep. Composite score = mean of 5 items. Range 0-100; higher scores indicate better sleep quality. |
| Secondary | Change in preoperative anxiety | From 60 minutes pre-surgery to immediately before induction | Measured as the change in the Visual Analogue Scale for Anxiety (VAS-A), a 100 mm horizontal analogue scale. Range 0-100 mm; 0 = no anxiety, 100 = worst possible anxiety. Change score = baseline VAS-A (T1) minus pre-induction VAS-A (T2). A positive value indicates reduction in anxiety; higher change scores indicate greater anxiolytic effect. |
| Secondary | Total opioid consumption | 0-24 hours postoperatively | expressed as intravenous morphine milligram equivalents (MME) |
| Secondary | Incidence of postoperative nausea and vomiting (PONV) | 0-24 hours postoperatively | postoperative nausea and vomiting (PONV) occurrence, Vomiting episodes, antiemetic rescue required |
| Secondary | Time to first rescue analgesic request | 0-24 hours postoperatively, measured in minutes from end of surgery | first rescue analgesic request within 24 hours postoperatively |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07553143
GET https://conductscience.org/api/trials/v1/NCT07553143/registered