Trial · NCT07555171
EEG Dynamics in Lennox-Gastaut Syndrome Patients Undergoing Fenfluramine Treatment
NCT07555171, Enrolling by invitation, University of Chicago
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. EEG Dynamics in Lennox-Gastaut Syndrome Patients Undergoing Fenfluramine Treatment. Trials, record NCT07555171. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07555171
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- EEG Dynamics in Lennox-Gastaut Syndrome Patients Undergoing Fenfluramine Treatment
- NCT number
- NCT07555171
- Status
- Enrolling by invitation
- Enrollment
- 20 participants, estimated
- Lead sponsor
- University of Chicago
- Conditions
- Lennox Gastaut Syndrome (LGS)
- Interventions
- fenfluramine HCl
- First posted
- 2026-04-29
- Last updated
- 2026-08-06
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Number of participants who have concordance between electroencephalogram (EEG) changes and clinical responsiveness in patients diagnosed with Lennox-Gastaut Syndrome (LGS) undergoing treatment with fenfluramine after 6 months. | from EEG prior to fenfluarmine initiation to follow up EEG 6 months after | |
| Secondary | Number of participants whose specific EEG biomarkers are predicative of clinical responsiveness to fenfluramine treatment before, during, and after fenfluramine treatment | from EEG prior to fenfluarmine initiation to follow up EEG 6 months after | |
| Secondary | Change from baseline differences of longitudinal EEG dynamics before and during fenfluramine therapy, including changes in background activity, paroxysmal fast activity, epileptiform discharges, and sleep architecture. | from EEG prior to fenfluarmine initiation to follow up EEG 6 months after | |
| Secondary | Number of clinical responders and non-responders to fenfluramine treatment measured by differences in quantitative EEG variables after 6 months | from EEG prior to fenfluramine initiation to follow up EEG 6 months after | |
| Secondary | Change from baseline in quality of life scores on the Ped-QL epilepsy or QL-Epilepsy after 6 months | from prior to EEG initiation to 6 months after |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07555171
GET https://conductscience.org/api/trials/v1/NCT07555171/registered