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Trial · NCT07555678

Chemoradiotherapy and Anti-PD-1 Antibody in Anal Squamous Cell Cancer:Chase

NCT07555678, Phase 2, Recruiting, Fudan University

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Chemoradiotherapy and Anti-PD-1 Antibody in Anal Squamous Cell Cancer:Chase. Trials, record NCT07555678. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07555678

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Chemoradiotherapy and Anti-PD-1 Antibody in Anal Squamous Cell Cancer:Chase
NCT number
NCT07555678
Status
Recruiting
Phases
Phase 2
Enrollment
241 participants, estimated
Lead sponsor
Fudan University
Conditions
Anal Squamous Cell Cancer
Interventions
PD-1 Inhibitor + Chemotherapy
First posted
2026-04-29
Last updated
2026-04-29

Source ClinicalTrials.gov

Registered outcomes3

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryComplete response rate1 month after the surgery or the decision of Watch and waitthe primary endpoint of cohort 3 is CR rate including cCR and pCR
PrimarySevere acute toxicity.from the start of radiotherapy to 3 months after the start of radiotherapyThe primary endpoint for Cohort 1 (early anal squamous cell carcinoma) and Cohort 2 (post-local excision anal squamous cell carcinoma) is the rate of severe adverse events.
Primary12-month progression-free survival (PFS).The proportion of patients who were alive and progression-free from the start of initial treatment up to 12 months.The primary endpoint for Cohort 4 (recurrent or metastetic anal squamous cell carcinoma) is 12-month progression-free survival (PFS).

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07555678

GET https://conductscience.org/api/trials/v1/NCT07555678/registered