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Trial · NCT07573163

Tirzepatide Following Adrenalectomy in Mild Autonomous Cortisol Secretion

NCT07573163, Phase 2, Recruiting, Alaa Sada

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Tirzepatide Following Adrenalectomy in Mild Autonomous Cortisol Secretion. Trials, record NCT07573163. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07573163

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Tirzepatide Following Adrenalectomy in Mild Autonomous Cortisol Secretion
NCT number
NCT07573163
Status
Recruiting
Phases
Phase 2
Enrollment
34 participants, estimated
Lead sponsor
Alaa Sada
Conditions
Mild Autonomous Cortisol Secretion (MACS), Adrenalectomy; Status
Interventions
Tirzepatide, Standard medical treatment
First posted
2026-05-07
Last updated
2026-07-30

Source ClinicalTrials.gov

Registered outcomes6

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryChange in systolic blood pressureBaseline and 12 monthsChanges in blood pressure will be assessed based on patients' average blood pressure readings, mmHg
SecondaryweightBaseline and 12 monthsChange in participant weight, Kg
SecondarymedicationBaseline and 12 months reported in WHO defined daily doses (DDDs)any change in medication expressed as defined daily doses (DDDs)
SecondaryHbA1cBaseline and 12 monthschange in HbA1c levels
Secondaryquality of life metricsBaseline and 12 months
quality of life metrics will measured using the 36-Item Short Form Health Survey (SF-36) which is a validated measure of health-related quality of life assessing eight domains: physical functioning, role-physical, bodily pain, general health, vitality, social functioning, role-emotional, and mental health. Each domain is scored from 0 to 100, with higher scores indicating better health status. Domain scores may be analyzed individually or combined using standard scoring algorithms to generate the Physical Component Summary (PCS) and Mental Component Summary (MCS) scores, which are norm-based (mean 50, SD 10); higher values reflect better physical and mental health, respectively.
SecondaryBMIBaseline and 12 monthsAny change in BMI in kg/m2

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers17

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
19632967BACKGROUNDPubMed
29963828BACKGROUNDPubMed
31900474BACKGROUNDPubMed
32206602BACKGROUNDPubMed
33017843BACKGROUNDPubMed
33065059BACKGROUNDPubMed
33528757BACKGROUNDPubMed
34260734BACKGROUNDPubMed
34978855BACKGROUNDPubMed
35799460BACKGROUNDPubMed

1 to 10 of 17

See all 17 papers

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07573163

GET https://conductscience.org/api/trials/v1/NCT07573163/registered