Trial · NCT07578558
NAI for Sepsis With Persistent Lymphopenia
NCT07578558, Phase 2, Not yet recruiting, ImmunityBio, Inc.
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. NAI for Sepsis With Persistent Lymphopenia. Trials, record NCT07578558. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07578558
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- NAI for Sepsis With Persistent Lymphopenia
- NCT number
- NCT07578558
- Status
- Not yet recruiting
- Phases
- Phase 2
- Enrollment
- 50 participants, estimated
- Lead sponsor
- ImmunityBio, Inc.
- Conditions
- Sepsis, Septic Shock, Lymphopenia, Immunosuppression, Critical Illness
- Interventions
- Nogapendekin alfa inbakicept (NAI), Standard of Care (SOC)
- First posted
- 2026-05-11
- Last updated
- 2026-05-11
Source ClinicalTrials.gov
Registered outcomes6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | 28-day all-cause mortality rate | 28 days | Proportion of participants who die from any cause within 28 days of randomization |
| Secondary | Change in absolute lymphocyte count (ALC) | Baseline through Day 28 | Change in ALC from baseline (Day 1 pre-dose) through Day 28 |
| Secondary | ICU re-admission rate | Up to Day 90 | Proportion of participants re-admitted to ICU after discharge by Day 90 |
| Secondary | Secondary infections | Up to Day 90 | Proportion of participants with secondary infections after discharge by Day 90 |
| Secondary | 90-day all-cause mortality rate | 90 days | Proportion of participants who die from any cause within 90 days of randomization |
| Secondary | Safety and tolerability | Through Day 30 after last dose | Incidence and severity of treatment-emergent adverse events (TEAEs), serious adverse events (SAEs), and Grade ≥3 TEAEs graded per NCI CTCAE v6.0 |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07578558
GET https://conductscience.org/api/trials/v1/NCT07578558/registered