Trial · NCT07587450
Efficacy of Non Operative Treatment With Amoxicillin/Clavulanic Acid Versus Surgical Treatment in Acute Uncomplicated Appendicitis in Children
NCT07587450, Phase 3, Not yet recruiting, University Hospital, Toulouse
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Efficacy of Non Operative Treatment With Amoxicillin/Clavulanic Acid Versus Surgical Treatment in Acute Uncomplicated Appendicitis in Children. Trials, record NCT07587450. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07587450
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Efficacy of Non Operative Treatment With Amoxicillin/Clavulanic Acid Versus Surgical Treatment in Acute Uncomplicated Appendicitis in Children
- NCT number
- NCT07587450
- Status
- Not yet recruiting
- Phases
- Phase 3
- Enrollment
- 724 participants, estimated
- Lead sponsor
- University Hospital, Toulouse
- Conditions
- Acute Uncomplicated Appendicitis
- Interventions
- Amoxi Clavulanate, appendicectomy
- First posted
- 2026-05-14
- Last updated
- 2026-05-22
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Percentage of treatment-related failures at one year | 12 months | readmissions for suspicion of appendicitis, secondary surgery, emergency visits related to appendicitis management, postoperative infections, side effects of antibiotics, adverse events of anesthesia. In surgery group, a normal appendix based on pathology or a complication requiring a new general anaesthesia |
| Secondary | Initial success rate | Day 12 | |
| Secondary | Score of quality of life with the questionnaire EQ-5D-Y-3L for children | Day 1, Month 1 and Month 12. | 0 is the worst score and 1 the better score (it is possible to have very bad values under 0) |
| Secondary | Score of of quality of life with the questionnaire EQ-5D-5L for parents | Day 1, Month 1 and Month 12. | 0 is the worst score and 1 the better score (it is possible to have very bad values under 0) |
| Secondary | Direct Medical costs, and indirect costs (parental absenteeism) descriptions | Month 12 | |
| Secondary | Rehospitalization, appendectomy | from Day 1 to Year 5 | Using consumption data available in SNDS database, describe child care pathways over 5 years |
| Secondary | Incidence of adverse events | At Month 1 and Month 12 | in the two groups, and incidence of adverse events due to antibiotics in the NOT group |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07587450
GET https://conductscience.org/api/trials/v1/NCT07587450/registered