Validation of Population Characteristics and Dosage Prescriptions for Cognitive Function Intervention Benefits of Different Doses of Tai Chi in Elderly Patients With Mild Cognitive Impairment: A Real-World Cross-Sectional Study
NCT07608510, Not yet recruiting, Lidian Chen
Trial 9
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Validation of Population Characteristics and Dosage Prescriptions for Cognitive Function Intervention Benefits of Different Doses of Tai Chi in Elderly Patients With Mild Cognitive Impairment: A Real-World Cross-Sectional Study | ClinicalTrials.gov |
| NCT number | NCT07608510 | ClinicalTrials.gov |
| Status | Not yet recruiting | ClinicalTrials.gov |
| Enrollment | 150 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | Lidian Chen | ClinicalTrials.gov |
| Conditions | Mild Cognitive Impairment (MCI) | ClinicalTrials.gov |
| Interventions | 24-form Simplified Tai Chi (Observational Behavioral Exposure) | ClinicalTrials.gov |
| First posted | 2026-05-27 | ClinicalTrials.gov |
| Last updated | 2026-05-27 | ClinicalTrials.gov |
Registered outcomes 14
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Montreal Cognitive Assessment | Single cross-sectional assessment at the time of study enrollment (baseline visit) | Global cognition | ClinicalTrials.gov |
| Secondary | Wechsler Memory Scale | Single cross-sectional assessment at the time of study enrollment (baseline visit) | Memory function | ClinicalTrials.gov |
| Secondary | Digital Symbol test | Single cross-sectional assessment at the time of study enrollment (baseline visit) | Attention | ClinicalTrials.gov |
| Secondary | Trial Making Test part B | Single cross-sectional assessment at the time of study enrollment (baseline visit) | Executive function | ClinicalTrials.gov |
| Secondary | Stroop color word test | Single cross-sectional assessment at the time of study enrollment (baseline visit) | Processing speed | ClinicalTrials.gov |
| Secondary | Boston naming test | Single cross-sectional assessment at the time of study enrollment (baseline visit) | Verbal fluency | ClinicalTrials.gov |
| Secondary | Rey-Osterrieth complex graphics test | Single cross-sectional assessment at the time of study enrollment (baseline visit) | ClinicalTrials.gov | |
| Secondary | Rey Auditory Verbal Learning Test | Single cross-sectional assessment at the time of study enrollment (baseline visit) | Episodic memory | ClinicalTrials.gov |
| Other | Blood glucose metabolism index | Single cross-sectional assessment at the time of study enrollment (baseline visit) | fasting blood glucose | ClinicalTrials.gov |
| Other | Blood lipid metabolism index | Single cross-sectional assessment at the time of study enrollment (baseline visit) | total cholesterol (TC), total triglyceride (TG), low density lipoprotein (LDL), high density lipoprotein (HDL) | ClinicalTrials.gov |
| Other | Resting-State Functional Magnetic Resonance Imaging: Default Mode Network Functional Connectivity Structural Magnetic Resonance Imaging: Hippocampal Volume | Single cross-sectional assessment at the time of study enrollment (baseline visit) | Resting-State Functional Magnetic Resonance Imaging (rs-fMRI) Measurement of Default Mode Network Functional Connectivity Strength Resting-state fMRI (rs-fMRI) data will be acquired using a 3.0T scanner to evaluate default mode network (DMN) functional connectivity strength, a key correlate of cognitive function. All scanning parameters, preprocessing and analysis methods are identical to our parent randomized controlled trials (FujianUTCM-1/2). Data processing uses SPM12 and CONN toolbox. 3.0T Three-Dimensional T1-Weighted Structural MRI (sMRI) Measurement of Bilateral Hippocampal Total Volume 3D T1-weighted structural MRI (sMRI) data will be acquired using a 3.0T scanner to quantify bilateral hippocampal total volume. All scanning parameters, preprocessing and volumetric analysis methods are consistent with our parent randomized controlled trials (FujianUTCM-1/2). Automated segmentation uses FreeSurfer 7.4.1 with manual visual correction. | ClinicalTrials.gov |
| Other | Core Peripheral Blood Biomarkers for Mild Cognitive Impairment (MCI) | Single cross-sectional assessment at the time of study enrollment (baseline visit) | Amyloid-beta(Aβ)、phosphorylated tau(p-tau)、Neurofilament light chain(NfL)、Glial fibrillary acidic protein(GFAP) | ClinicalTrials.gov |
| Other | Pittsburgh Sleep Quality Index, PSQI | Single cross-sectional assessment at the time of study enrollment (baseline visit) | Sleep Quality | ClinicalTrials.gov |
| Other | 12-Item Short Form Health Survey | Single cross-sectional assessment at the time of study enrollment (baseline visit) | General health | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 4
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Picture Naming Test | Secondary outcome | ConductCognition |
| Stroop Color-Word Test | Secondary outcome | ConductCognition |
| Verbal Fluency | Secondary outcome | ConductCognition |
| Verbal Learning | Secondary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)