Effects of Bicarbonate Spring Water Immersion on Cognitive Reliability and Post-Maximal Exercise Recovery in Adolescent Rowers During Altitude Training: A Sex-Stratified Three-Arm Randomized Controlled Trial
NCT07608913, Not applicable, Completed, Macao Polytechnic University
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Effects of Bicarbonate Spring Water Immersion on Cognitive Reliability and Post-Maximal Exercise Recovery in Adolescent Rowers During Altitude Training: A Sex-Stratified Three-Arm Randomized Controlled Trial | ClinicalTrials.gov |
| NCT number | NCT07608913 | ClinicalTrials.gov |
| Status | Completed | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 27 participants, actual | ClinicalTrials.gov |
| Lead sponsor | Macao Polytechnic University | ClinicalTrials.gov |
| Conditions | Altitude Training Adaptation, Cognitive Function, Cerebral Hemodynamics, Exercise Performance, Hydrotherapy, Balneotherapy, Hypoxia | ClinicalTrials.gov |
| Interventions | Control Group：Natural Recovery, Hot water immersion group, hot spring immersion group | ClinicalTrials.gov |
| First posted | 2026-05-27 | ClinicalTrials.gov |
| Last updated | 2026-08-04 | ClinicalTrials.gov |
Registered outcomes 7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Psychomotor Vigilance Test (PVT) | Baselines were measured at the formal start of the experiment, at night during the 2nd, 3rd, and 4th weeks (post-intervention) after ascending the plateau, and post-tests were conducted one week after descending the plateau. | 5-minute PVT measuring sustained attention and psychomotor vigilance. Outcome variables: mean reciprocal response time (1/RT). Administered via standardized software on a tablet/computer. Unit: second. | ClinicalTrials.gov |
| Primary | Stroop Test Performance | Baselines were measured at the formal start of the experiment, at night during the 2nd, 3rd, and 4th weeks (post-intervention) after ascending the plateau, and post-tests were conducted one week after descending the plateau. | Computerized Stroop Color-Word Test measuring executive function and cognitive inhibition. Outcome variables: reaction time (ms). Administered in a quiet, temperature-controlled room (22-24°C). Unit: milliseconds (ms). | ClinicalTrials.gov |
| Primary | Cerebral Oxygenation (fNIRS) | Baseline, Week 2, Week 5 | Changes in oxygenated hemoglobin (HbO) and deoxygenated hemoglobin (HbR) in the prefrontal cortex during cognitive tasks, measured by functional near-infrared spectroscopy (fNIRS) with a multichannel system. Outcome: relative changes in HbO and HbR concentrations. Unit: micromolar (μM). | ClinicalTrials.gov |
| Primary | Cerebral Blood Flow Velocity (TCD) | Baseline, Week 2, Week 4 | Mean blood flow velocity in the middle cerebral artery (MCA) and anterior cerebral artery (ACA) measured by transcranial Doppler ultrasound (TCD) with 2MHz probe. Measurements taken in supine position after 10 minutes of rest. Outcome: mean velocity (cm/s). Unit: centimeters/second (cm/s). | ClinicalTrials.gov |
| Secondary | Maximal Oxygen Uptake (VO2max) | Baseline, Week 5 | Maximal oxygen uptake measured using a portable metabolic analyzer during a graded exercise test on a rowing ergometer. Test protocol: incremental ramp test to exhaustion. Unit: mL/kg/min. | ClinicalTrials.gov |
| Secondary | 1000-Meter Running Test | Baseline, Week 3, Week4 | 1000-meter maximal effort running test on a standard 400m track or treadmill. Total completion time recorded. Unit: seconds (s). | ClinicalTrials.gov |
| Secondary | Peripheral Oxygen Saturation (SpO2) | one month. | Resting peripheral oxygen saturation measured via fingertip pulse oximeter after 10 minutes of seated rest. Unit: percentage (%). | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 6
The papers the trial lists on ClinicalTrials.gov.
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 2
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Psychomotor Vigilance Task | Primary outcome | ConductCognition |
| Stroop Color-Word Test | Primary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)