Trial · NCT07615478
Effect of Hot Spring Therapy on Central Fatigue Elimination During Altitude Training
NCT07615478, Not applicable, Recruiting, Macao Polytechnic University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Effect of Hot Spring Therapy on Central Fatigue Elimination During Altitude Training. Trials, record NCT07615478. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07615478
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Effect of Hot Spring Therapy on Central Fatigue Elimination During Altitude Training
- NCT number
- NCT07615478
- Status
- Recruiting
- Phases
- Not applicable
- Enrollment
- 27 participants, estimated
- Lead sponsor
- Macao Polytechnic University
- Conditions
- Central Fatigue, Altitude Training, Cognitive Impairment, Hydrotherapy, Balneotherapy, Sports Performance
- Interventions
- Natural recovery, Hot water immersion, Hot spring balneotherapy
- First posted
- 2026-05-29
- Last updated
- 2026-05-29
Source ClinicalTrials.gov
Registered outcomes8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Voluntary Activation | Baseline (Week 0), Week 2, Week 3, Week 4 (post-intervention), Follow-up (Week 1-2 post-altitude) | Voluntary activation assessed by the interpolated twitch technique (ITT) during maximal voluntary contraction (MVC) of the quadriceps femoris using percutaneous electrical stimulation. A single stimulus is superimposed on MVC; VA is calculated as: VA = (1 - superimposed twitch force / potentiated resting doublet force) × 100%. Higher VA indicates greater central neural drive. Unit: percentage (%). |
| Primary | Central Activation Ratio | Baseline (Week 0), Week 2, Week 3, Week 4, Follow-up (Week 5-6 post-altitude) | Central activation ratio measured as the ratio of maximal voluntary contraction force to the force evoked by supramaximal electrical stimulation of the femoral nerve during quadriceps contraction. CAR = MVC force / (MVC force + superimposed twitch force). Values closer to 1.0 indicate less central fatigue. Unit: ratio (0-1, no units). |
| Secondary | Stroop Test Performance | Baseline, Week 2,Week 4, Follow-up (Week 1-2 post-altitude) | Computerized Stroop Color-Word Test measuring executive function and cognitive inhibition. Outcome variables: reaction time (ms) for congruent and incongruent trials, with interference effect calculated as incongruent minus congruent reaction time. Administered in a quiet, temperature-controlled room (22-24°C). Unit: milliseconds (ms). |
| Secondary | Cerebral Oxygenation | Baseline, Week 2, fellow up | Changes in oxygenated hemoglobin (HbO2) and deoxygenated hemoglobin (Hb) in the prefrontal cortex during rest and cognitive tasks, measured by functional near-infrared spectroscopy (fNIRS) with a multichannel system. Outcome: relative concentration changes (ΔμM) in HbO2 and Hb from baseline. Unit: micromolar (μM). |
| Secondary | Psychomotor Vigilance Test | Baseline, Week 2, Week 3, Week 4, Follow-up (Week 1-2 post-altitude) | 5-minute Psychomotor Vigilance Test measuring sustained attention and psychomotor vigilance. Outcome variables: mean response time, and number of lapses (reaction time \>500 ms). Administered via standardized software on a tablet/computer in a quiet environment. Unit: milliseconds (ms). |
| Secondary | Maximal Oxygen Uptake (VO2max) | Baseline (Week 0), Follow-up (Week 5-6 post-altitude) | Maximal oxygen uptake measured during a graded exercise test on a rowing ergometer using a portable metabolic cart. Protocol: incremental ramp test (starting at 100W, increasing 20W every 2 minutes) until volitional exhaustion. Unit: mL/kg/min. |
| Secondary | White Blood Cell Count (WBC) | Baseline, Week 2, Follow up (Week 5-6 post-altitude) | Total white blood cell count measured from fasting venous blood sample using automated hematology analyzer. Unit: 10\^9 cells per liter (10\^9/L). |
| Secondary | Neutrophil Count (NEUT) | Baseline, Week 2, Follow-up (Week 5-6 post-altitude) | Absolute neutrophil count measured from fasting venous blood sample using automated hematology analyzer. Unit: 10\^9/L. Baseline, Week 4 11 Platelet Count (PLT) Platelet count measured from fasting venous blood sample using automated hematology analyzer. Unit: 10\^9/L. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers7
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests2
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Psychomotor Vigilance Task | Secondary outcome | ConductCognition |
| Stroop Color-Word Test | Secondary outcome | ConductCognition |
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07615478
GET https://conductscience.org/api/trials/v1/NCT07615478/registered