Walking and Thinking - Brain Activity During Complex Walking in Stroke
NCT07624630, Recruiting, Karolinska Institutet
Trial 9
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Walking and Thinking - Brain Activity During Complex Walking in Stroke | ClinicalTrials.gov |
| NCT number | NCT07624630 | ClinicalTrials.gov |
| Status | Recruiting | ClinicalTrials.gov |
| Enrollment | 50 participants, estimated | ClinicalTrials.gov |
| Lead sponsor | Karolinska Institutet | ClinicalTrials.gov |
| Conditions | Stroke, Aging, Neuro-Degenerative Disease, Gait Impairment in Stroke Patients | ClinicalTrials.gov |
| Interventions | No Interventions | ClinicalTrials.gov |
| First posted | 2026-06-03 | ClinicalTrials.gov |
| Last updated | 2026-06-03 | ClinicalTrials.gov |
Registered outcomes 18
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Functional near infrared spectrometry (fNIRS) | Baseline | The measurement of changes in concentration of oxygenated hemoglobin (HbO) and deoxygenated hemoglobin (HHb) in the prefrontal cortex will be assessed using a NIRSPORT 2 (NIRx Medizintechnik, Berlin, Germany) device. | ClinicalTrials.gov |
| Primary | Stride time during all conditions | Baseline | Stride time will be analyzed with the APDM mobility system. | ClinicalTrials.gov |
| Primary | Velocity during all conditions | Baseline | Velocity will be analyzed with the APDM mobility system. | ClinicalTrials.gov |
| Primary | Dual-task performance-reaction time | Baseline | Cognitive performance of the dual task will be assessed as errors in the response to the Auditory stroop task. | ClinicalTrials.gov |
| Secondary | Cognitive performance | Baseline | Global cognitive performance will be assessed with the Montreal Cognitive Assessment (MoCA). Scores range from 0-30, with higher score indicating better performance. | ClinicalTrials.gov |
| Secondary | Stroke severity | Baseline | Assessed using the National Institutes of Health Stroke Scale (NIHSS). Scores range from 0-42, with higher scores indicating greater stroke severity. | ClinicalTrials.gov |
| Secondary | Stroke specific health status | Baseline | Assessed using the Stroke Impact Scale (SIS). Scores range from 0-100, with higher scores indicating better functioning | ClinicalTrials.gov |
| Secondary | Physical Impairment | Baseline | Assessed using the Chedoke McMaster Stroke Assessment. Scores range from 1-7 for each impairment dimension, with higher scores indicating better motor recovery. | ClinicalTrials.gov |
| Secondary | Walking ability | Baseline | Assessed using the Walk-12G. Scores range from 0-42, with higher scores indicating greater walking difficulties | ClinicalTrials.gov |
| Secondary | Balance performance | Baseline | Assessed with the Mini-BESTest (Balance Evaluation Systems test). Scores range from 0-28, with higher scores indicating better balance performance. | ClinicalTrials.gov |
| Secondary | Anxiety and Deprssion | Baseline | Assessed with Hospital Anxiety and Depression Scale (HADS). Scores range from 0-24 for the anxiety and depression subscales, respectively, with lower scores indicating fewer symptoms of anxiety and depression | ClinicalTrials.gov |
| Secondary | Cognitive function - Attention and psychomotor processing speed | Baseline | Attention and psychomotor processing speed will be assessed with the Trail Making Test (TMT) from D-KEFS (Delis-Kaplan Executive Function System). | ClinicalTrials.gov |
| Secondary | Cognitive function - Episodic memory | Baseline | Episodic memory will be assessed with the Ray Auditory Verbal Learning Test (RAVLT). | ClinicalTrials.gov |
| Secondary | Self-reported level of physical activity | Baseline | Assessed with the Frändin-Grimby Scale. Scores range from 1-6, with higher scores indicating higher levels of physical activity. | ClinicalTrials.gov |
| Secondary | Cognitive function - verbal fluency | Baseline | Verbal function, initiation \& task-set switching with the Verbal Fluency test from D-KEFS (Delis-Kaplan Executive Function System). | ClinicalTrials.gov |
| Secondary | Physical activity levels | Baseline | Assessed with acceleromters (Actigraph GT3X+) | ClinicalTrials.gov |
| Secondary | Dual-task performance -errors | Baseline | Cognitive performance of the dual task will be assessed as the reaction time to respond during Auditory stroop | ClinicalTrials.gov |
| Secondary | Navigation errors | Baseline | Assessed using a GoPro camera | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 5
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Stroop Color-Word Test | Primary outcome | ConductCognition |
| Trail Making Test A | Secondary outcome | ConductCognition |
| Trail Making Test B | Secondary outcome | ConductCognition |
| Verbal Fluency | Secondary outcome | ConductCognition |
| Verbal Learning | Secondary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)