Harmonization of Teleneuropsychological Assessment in Dementia
NCT07664865, Completed, IRCCS National Neurological Institute "C. Mondino" Foundation
Trial 8
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Harmonization of Teleneuropsychological Assessment in Dementia | ClinicalTrials.gov |
| NCT number | NCT07664865 | ClinicalTrials.gov |
| Status | Completed | ClinicalTrials.gov |
| Enrollment | 250 participants, actual | ClinicalTrials.gov |
| Lead sponsor | IRCCS National Neurological Institute "C. Mondino" Foundation | ClinicalTrials.gov |
| Conditions | Cognitive Impairment | ClinicalTrials.gov |
| First posted | 2026-06-24 | ClinicalTrials.gov |
| Last updated | 2026-06-24 | ClinicalTrials.gov |
Registered outcomes 21
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Collecting normative data | At baseline | Administration of the tablet-based battery to a sample of healthy subjects in a single session lasting approximately 45/60 minutes (Phase 1 objective) | ClinicalTrials.gov |
| Primary | Free and Cued Selective Reminding Test (FCSRT) | At baseline | Verbal episodic memory assessed by the FCSRT. The digital version includes 16 words presented in four sets of four items. Free recall scores range from 0 to 48 and total recall scores range from 0 to 48. Higher scores indicate better verbal leraning and memory performance. | ClinicalTrials.gov |
| Primary | Spatial Supraspan | At baseline | Visuospatial working memory assessed by the Spatial Supraspan test. Participants are required to reproduce increasingly longer spatial sequences presented on the tablet. Higher scores indicate better visuospatial memory performance. | ClinicalTrials.gov |
| Primary | Rey-Osterrieth Complex Figure Delayed Recall | At baseline | Visual episodic memory assessed by the Rey-Osterrieth Complex Figure delayed recall task. Scores range from 0 to 36. Higher scores indicate better visual memory performance. | ClinicalTrials.gov |
| Primary | Phonemic and Semantic Verbal Fluency | At baseline | Language and executive functioning assessed through phonemic and semantic verbal fluency tasks. Participants are required to generate words belonging to a semantic category or beginning with a target letter within a fixed time interval. The score corresponds to the number of correct words produced. Higher scores indicate better language and executive functioning. | ClinicalTrials.gov |
| Primary | Complex Picture Description Test | At baseline | Spontaneous speech production assessed using the complex picture description task from the Screening of Aphasia in NeuroDegeneration (SAND) battery. The score is based on the number of nouns, verbs and complete sentences produced. Higher scores indicate better language production abilities. | ClinicalTrials.gov |
| Primary | Picture Naming Test | At baseline | Lexical-semantic abilities assessed by a picture naming task including 16 coloured living and non-living objects. Scores range from 0 to 16. Higher scores indicate better naming performance and lexical retrieval abilities. | ClinicalTrials.gov |
| Primary | Rey-Osterrieth Complex Figure Copy | At baseline | Visuoconstructional abilities assessed by the Rey-Osterrieth Complex Figure copy task. Scores range from 0 to 36. Higher scores indicate better visuospatial and constructional abilities. | ClinicalTrials.gov |
| Primary | Pentagon Copying Test | At baseline | Visuoconstructional abilities assessed through copying intersecting pentagons. Higher scores indicate better visuospatial and constructional performance. | ClinicalTrials.gov |
| Primary | Clock Drawing Test | At baseline | Visuospatial and executive functioning assessed by the Clock Drawing Test. Higher scores indicate better visuoconstructional and executive abilities. | ClinicalTrials.gov |
| Primary | Symbol Digit Modalities Test (SDMT) | At baseline | Attention, processing speed and executive functioning assessed by the SDMT. The score corresponds to the number of correct symbol-digit associations completed within the allotted time. Higher scores indicate better cognitive processing speed and attention. | ClinicalTrials.gov |
| Primary | Stroop Test | At baseline | Executive functioning and inhibitory control assessed by the Stroop Test. Scores are based on response accuracy and interference effects across test conditions. Better performance is reflected by fewer errors and lower interference. | ClinicalTrials.gov |
| Primary | Emotion Recognition Test | At baseline | Social cognition assessed by the Emotion Recognition Test. The digital version includes 28 facial stimuli depicting basic emotions and neutral expressions. Scores range from 0 to 28. Higher scores indicate better recognition of facial emotions and social cognitive functioning. | ClinicalTrials.gov |
| Primary | Geriatric Depression Scale (GDS-15) | At baseline | Depressive symptoms assessed by the 15-item GDS. Scores range from 0 to 15. Higher scores indicate more severe depressive symptoms. A score of 5 or greater suggests clinically relevant depressive symptoms. | ClinicalTrials.gov |
| Primary | Activities of Daily Living (ADL) | At baseline | Basic functional independence assessed by the ADL scale. Scores range from 0 to 6. Higher scores indicate greater independence in daily functioning. | ClinicalTrials.gov |
| Primary | Instrumental Activities of Daily Living (IADL) | At baseline | Functional independence in complex daily activities assessed by the IADL scale. Scores range from 0 to 8. Higher scores indicate greater functional independence. | ClinicalTrials.gov |
| Secondary | Learning and Memory: FCSRT, Spatial Supraspan, Rey-Osterrieth Complex Figure Delayed Recall. | At baseline | Scores obtained on the FCSRT, Spatial Supraspan, and Rey-Osterrieth Complex Figure Delayed Recall, which assess learning and memory abilities. Correlations between test scores will be examined separately in healthy controls and patients. | ClinicalTrials.gov |
| Secondary | Language: Picture Naming Test, Phonemic and Semantic Verbal Fluency, Complex Picture Description Test. | At baseline | Scores obtained on the Picture Naming test, Phonemic and Semantic Verbal Fluency, and Complex Picture Description Test, which assess language abilities. Correlations between test scores will be examined separately in healthy controls and patients. | ClinicalTrials.gov |
| Secondary | Visuo-perceptual and Constructional Skills: Rey-Osterrieth Complex Figure Copy, Pentagon Copying Test, Clock Drawing Test. | At baseline | Scores obtained on the Rey-Osterrieth Complex Figure Copy, Pentagon Copying Test, and Clock Drawing Test, which assess visuoperceptual and constructional abilities. Correlations between test scores will be examined separately in healthy controls and patients. | ClinicalTrials.gov |
| Secondary | Attention and Executive Functions: SDMT, Stroop Test. | At baseline | Scores obtained on the SDMT and Stroop Test, which assess attention, processing speed, inhibitory control, and executive functioning. Correlations between test scores will be examined separately in healthy controls and patients. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 18
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|---|---|
| 21514249 | BACKGROUND | PubMed |
| 21514250 | BACKGROUND | PubMed |
| 22382386 | BACKGROUND | PubMed |
| 28155182 | BACKGROUND | PubMed |
| 31248465 | BACKGROUND | PubMed |
| 32440979 | BACKGROUND | PubMed |
| 32519594 | BACKGROUND | PubMed |
| 32666093 | BACKGROUND | PubMed |
| 32844714 | BACKGROUND | PubMed |
| 33300414 | BACKGROUND | PubMed |
| 33314910 | BACKGROUND | PubMed |
| 33388003 | BACKGROUND | PubMed |
| 33927583 | BACKGROUND | PubMed |
| 33984176 | BACKGROUND | PubMed |
| 34573267 | BACKGROUND | PubMed |
| 34937315 | BACKGROUND | PubMed |
| 35982477 | BACKGROUND | PubMed |
| 36873886 | BACKGROUND | PubMed |
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 8
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Clock Drawing Task | Primary outcome | ConductCognition |
| Complex Figure Copy and Recall | Primary outcome | ConductCognition |
| Emoji Emotion Recognition | Primary outcome | ConductCognition |
| Picture Naming Test | Primary outcome | ConductCognition |
| Selective Reminding Task | Primary outcome | ConductCognition |
| Stroop Color-Word Test | Primary outcome | ConductCognition |
| Symbol Coding | Primary outcome | ConductCognition |
| Verbal Fluency | Primary outcome | ConductCognition |
Source 4
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.3.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 4a570df2e7274cee2d4fa2959402fab41880e2cd412e4b590390035fbea69391 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
Release trials-2026-11-12-0.3.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.