Whole-Body Vibration in Parkinson Disease
NCT07678983, Not applicable, Active not recruiting, Izmir Bakircay University
Trial 10
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
| Field | Value | Source |
|---|---|---|
| Title | Whole-Body Vibration in Parkinson Disease | ClinicalTrials.gov |
| NCT number | NCT07678983 | ClinicalTrials.gov |
| Status | Active not recruiting | ClinicalTrials.gov |
| Phases | Not applicable | ClinicalTrials.gov |
| Enrollment | 66 participants, actual | ClinicalTrials.gov |
| Lead sponsor | Izmir Bakircay University | ClinicalTrials.gov |
| Conditions | Parkinson's Disease, Balance, Gait, Cognitive Function, Dual-Task Performance, Reaction Time | ClinicalTrials.gov |
| Interventions | Functional Exercise Based Physiotherapy, Low-Frequency Whole-Body Vibration Therapy, Medium-Frequency Whole-Body Vibration Therapy | ClinicalTrials.gov |
| First posted | 2026-07-01 | ClinicalTrials.gov |
| Last updated | 2026-07-14 | ClinicalTrials.gov |
Registered outcomes 9
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description | Source |
|---|---|---|---|---|
| Primary | Mini Balance Evaluation Systems Test (Mini-BESTest) | Baseline and 8 weeks | Participants will be assessed while standing on a flat and firm surface. During the test, appropriate safety precautions will be taken if necessary to ensure participant safety. The assessment includes 4 subcomponents and 14 items: anticipatory postural adjustments, reactive postural control, sensory orientation, and dynamic gait. Each subcomponent represents different aspects of balance control and evaluates specific components of the postural control system. In each section of the assessment, participants will be asked to perform various functional tasks, and their performance will be observed during these tasks. The tasks include sit-to-stand and stand-to-sit transitions, standing balance, forward reach, backward stepping, standing with eyes closed, and turning while walking. Each item is scored on a 0-2 scale (0 = Severe İmpairment, 1 = Moderate İmpairment, 2 = Normal/No İmpairment), with a total score ranging from 0 to 28. | ClinicalTrials.gov |
| Primary | 10 Meter Walk Test (10MWT) | Baseline and 8 weeks | Participants will be assessed while standing on a flat, firm, and non-slip surface. Participants will be asked to walk a 14 meter walkway, with the central 10 meter section used for timing. Walking speed will be recorded over this 10 meter distance. The test will be performed under two conditions: comfortable walking speed and maximum walking speed, with two trials for each condition. Completion time will be measured using a stopwatch, and walking speed will be calculated and expressed as meters per second (m/s) based on the average of the trials. | ClinicalTrials.gov |
| Secondary | Verbal Fluency Test | Baseline and 8 weeks | The test will be administered in two conditions: Semantic (Category) Fluency and Phonemic (Letter) Fluency. In the semantic fluency task, participants will be asked to generate as many words as possible belonging to a specific category (E.g., "Animals") within a given time period. In the phonemic fluency task, participants will be asked to produce as many words as possible beginning with a specific letter (E.g., "K") within a given time period. Each correct word that meets the criteria will be scored as 1 point. Repetitions, proper nouns, and responses that do not meet the specified criteria will be excluded from the scoring. | ClinicalTrials.gov |
| Secondary | Forward-Backward Digit Span Test | Baseline and 8 weeks | Participants will be presented with sequences of numbers with increasing length and will be asked to repeat them in the correct order (Forward) and in reverse order (Backward). In both sections, the number sequences will progressively increase in length (E.G., starting with 3 digits, then 4 digits, then 5 digits, etc.). If the participant makes an error, the trial will be terminated or the sequence length will be recorded as a failure for that level. Scoring will be based on the correctly reproduced digit sequences in forward and backward conditions or the longest correctly recalled sequence. Each correct response will be scored as 1 point, and both correct and incorrect responses will be recorded. | ClinicalTrials.gov |
| Secondary | Trail Making Test (TMT) | Baseline and 8 weeks | The test will be administered in two parts: Part A and Part B. In Part A, participants will be asked to connect numbers from 1 to 25 in ascending order as quickly as possible. In Part B, participants will be required to alternately connect numbers (1-13) and letters (A-L) in sequence (E.G., 1-A, 2-B, 3-C, etc.) as quickly and accurately as possible. For both parts, completion time, the difference between Part B and Part A (B-A), the B/A ratio, and the number of errors will be recorded. | ClinicalTrials.gov |
| Secondary | Stroop Color and Word Test | Baseline and 8 weeks | The test will be administered in three conditions: Stroop Part 1 (Word Reading), Stroop Part 2 (Color Naming), and Stroop Part 3 (Incongruent Word-Color Condition). In Part 1, participants will be presented with a list of color words and asked to read the words aloud. In Part 2, participants will be shown colored squares and asked to name the colors. In Part 3, participants will be presented with color words printed in incongruent ink colors and asked to name the ink color rather than reading the word. For all three parts, completion time, number of correct responses, and number of incorrect responses will be recorded. | ClinicalTrials.gov |
| Secondary | Dual-Task Gait Test | Baseline and 8 weeks | The test will be administered under three conditions: cognitive dual-task, motor dual-task, and mixed dual-task. Participants will perform the test while walking on a flat, firm, and non-slip surface. Initially, participants will be asked to walk at a normal pace. Subsequently, dual-task conditions will be introduced, requiring participants to perform an additional task while walking. In the cognitive dual-task condition, a cognitive task will be added during walking. In the motor dual-task condition, an additional motor task will be performed while walking. In the mixed dual-task condition, an additional task will be performed during turning while walking. Test duration (Seconds) will be recorded using a stopwatch. Dual-Task Cost (DTC) will be calculated using the following formula: DTC (%) = \[(single-task performance - dual-task performance) / single-task performance\] × 100. | ClinicalTrials.gov |
| Secondary | Dual-Task Timed Up and Go (TUG) Test | Baseline and 8 weeks | The test will be administered under three conditions: cognitive dual-task TUG, motor dual-task TUG, and mixed dual-task TUG. Participants will perform the test while seated on a standard chair placed on a flat, firm, and non-slip surface. In the standard condition, participants will be instructed to stand up from a chair, walk a set distance, turn around, walk back, and sit down again. Subsequently, dual-task conditions will be applied by adding an additional task during the TUG procedure. In the cognitive dual-task TUG, a cognitive task will be added during the test. In the motor dual-task TUG, an additional motor task will be included. In the mixed dual-task TUG, both cognitive and motor tasks will be performed simultaneously or task difficulty will be increased.Test completion time (Seconds) will be recorded using a stopwatch. Dual-Task Cost (DTC) will be calculated using the following formula: DTC (%) = \[(single-task performance - dual-task performance) / single-task perform | ClinicalTrials.gov |
| Secondary | Ruler Drop Test | Baseline and 8 weeks | The test will be administered under three conditions: simple, selective, and dual-task. Participants will be seated with the forearm supported on a table and the elbow flexed at 90 degrees. In the simple condition, participants will be instructed to catch a falling ruler as quickly as possible when it is released. In the selective condition, participants will be required to catch the ruler only when a specific stimulus is presented. In the dual-task condition, participants will perform an additional task simultaneously while attempting to catch the ruler. The distance between the point of ruler release and the point of catch will be recorded. A total of three trials will be performed, and both the best and mean values will be recorded. | ClinicalTrials.gov |
Outcomes 0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as | Source |
|---|
Results by group 0
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units | Source |
|---|
Participant flow 0
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted | Source |
|---|
Adverse events 0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events | Source |
|---|
Adverse event totals 0
The totals the trial posted for each group.
| Total | Group | Affected | At risk | Source |
|---|
Papers 0
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as | Source |
|---|
Grants 0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|
Trial comparisons 0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|
Tests 6
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| Category Fluency | Secondary outcome | ConductCognition |
| Digit Span Test | Secondary outcome | ConductCognition |
| Stroop Color-Word Test | Secondary outcome | ConductCognition |
| Trail Making Test A | Secondary outcome | ConductCognition |
| Trail Making Test B | Secondary outcome | ConductCognition |
| Verbal Fluency | Secondary outcome | ConductCognition |
Source 5
| Field | Value | Source |
|---|---|---|
| Release | trials-2026-11-12-0.4.0 | ClinicalTrials.gov |
| Release manifest SHA-256 | 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4 | ClinicalTrials.gov |
| Registry capture | 2026-11-12 | ClinicalTrials.gov |
| Results copy, AACT | 2026-03-23 | ClinicalTrials.gov |
| NIH clinical studies file | 2026-11-13 | ClinicalTrials.gov |
Release trials-2026-11-12-0.4.0
ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
NIH RePORTER's clinical studies and project files: Public domain (NIH RePORTER)