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Trial · NCT07877246

A Longitudinal Natural History Study of Immune Biomarkers in Neuropsychiatric Illness

NCT07877246, Recruiting, National Institute of Mental Health (NIMH)

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. A Longitudinal Natural History Study of Immune Biomarkers in Neuropsychiatric Illness. Trials, record NCT07877246. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07877246

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
A Longitudinal Natural History Study of Immune Biomarkers in Neuropsychiatric Illness
NCT number
NCT07877246
Status
Recruiting
Enrollment
5,000 participants, estimated
Lead sponsor
National Institute of Mental Health (NIMH)
Conditions
Neuropsychiatric Disorders, Neuroinflammatory Disorders, Post-Infectious Neuropsychiatric Disorders
First posted
2026-10-16
Last updated
2026-11-03

Source ClinicalTrials.gov

Registered outcomes2

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryIdentification of Recurrent Autoantibodies in Neuropsychiatric SubgroupsThrough study completion, up to 10 years
Identification of autoantibodies that are recurrently detected and statistically enriched (presence versus absence) in prespecified neuropsychiatric diagnostic or phenotypic subgroups compared with control participants.
SecondaryCorrelate these immune factors with endotypes and endophenotypes of diverse neuropsychiatric disorders.Through study completion, up to 10 yearsIdentification of biomarker signatures that reliably classify psychotic subgroups as distinct from controls.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers35

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
5606187BACKGROUNDPubMed
19442432BACKGROUNDPubMed
19812534BACKGROUNDPubMed
23941274BACKGROUNDPubMed
25168608BACKGROUNDPubMed
25695943BACKGROUNDPubMed
26183699BACKGROUNDPubMed
26196028BACKGROUNDPubMed
26906964BACKGROUNDPubMed
28759653BACKGROUNDPubMed

1 to 10 of 35

See all 35 papers

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07877246

GET https://conductscience.org/api/trials/v1/NCT07877246/papers?page=2