Trial · NCT07877350
Association of Inspiratory Effort With Dyspnea During Assisted Mechanical Ventilation in Critically Ill Patients
NCT07877350, Recruiting, University of Crete
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Association of Inspiratory Effort With Dyspnea During Assisted Mechanical Ventilation in Critically Ill Patients. Trials, record NCT07877350. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07877350
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Association of Inspiratory Effort With Dyspnea During Assisted Mechanical Ventilation in Critically Ill Patients
- NCT number
- NCT07877350
- Status
- Recruiting
- Enrollment
- 50 participants, estimated
- Lead sponsor
- University of Crete
- Conditions
- Dyspnea During Mechanical Ventilation, Inspiratory Effort, Mechanical Ventilation
- First posted
- 2026-10-16
- Last updated
- 2026-10-16
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Association between Pmean/Pmax and dyspnea intensity | At baseline and at each clinically indicated pressure-support level during the study observation session, approximately 5 minutes and 30-60 minutes after each adjustment | Association of Pmean/Pmax, calculated from recorded inspiratory-pressure waveforms and maximal inspiratory pressure, with dyspnea intensity assessed by a 0-10 numerical rating scale in communicative participants or by MV-RDOS in non-communicative participants. The association will be evaluated with repeated-measures mixed-effects modeling. |
| Primary | Comparative association of inspiratory-effort indices with dyspnea intensity | During each study observation session, an average of 2-6 hours | Comparison of the strength of association between dyspnea intensity and Pmean/Pmax versus P0.1, δPmus, and PTP. |
| Primary | Discrimination of clinically significant dyspnea by Pmean/Pmax | During each study observation session, an average 2-6 hours | Diagnostic/discriminative performance of Pmean/Pmax for clinically significant dyspnea, defined prospectively as numerical rating scale score greater than 4 in communicative participants and/or the prespecified MV-RDOS threshold in non-communicative participants. The optimal threshold will be estimated using receiver-operating-characteristic analysis. |
| Secondary | Prevalence of clinically significant dyspnea | During the study observation session | Proportion of participants with clinically significant dyspnea at any observed pressure-support level. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers20
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07877350
GET https://conductscience.org/api/trials/v1/NCT07877350/registered