Trial · NCT07879690
Impact of Restrictive Diets on Inflammation and Quality of Life in Autoimmune Thyroiditis
NCT07879690, Not applicable, Not yet recruiting, University of Barcelona
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Impact of Restrictive Diets on Inflammation and Quality of Life in Autoimmune Thyroiditis. Trials, record NCT07879690. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07879690
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Impact of Restrictive Diets on Inflammation and Quality of Life in Autoimmune Thyroiditis
- NCT number
- NCT07879690
- Status
- Not yet recruiting
- Phases
- Not applicable
- Enrollment
- 60 participants, estimated
- Lead sponsor
- University of Barcelona
- Conditions
- Thyroid Autoimmune Disease, Hashimoto's Thyroiditis, Graves Disease
- Interventions
- Gluten-free, casein-free, low-glycemic-index diet
- First posted
- 2026-10-19
- Last updated
- 2026-11-04
Source ClinicalTrials.gov
Registered outcomes15
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in serum anti-thyroid peroxidase (anti-TPO) antibody levels | Baseline (month 0) and month 12 | Serum anti-TPO antibodies (IU/mL) measured by immunoassay in a fasting morning blood sample. Change from baseline to month 12 is compared between groups. |
| Secondary | Change in serum anti-thyroglobulin (anti-Tg) antibody levels | Baseline, month 4, month 8 and month 12 | Serum anti-Tg antibodies (IU/mL) measured by immunoassay. |
| Secondary | Change in high-sensitivity C-reactive protein (hs-CRP) | Baseline, month 4, month 8 and month 12 | Serum hs-CRP (mg/L) measured by immunoturbidimetry or nephelometry. |
| Secondary | Change in erythrocyte sedimentation rate (ESR) | Baseline, month 4, month 8 and month 12 | ESR (mm/h) measured by the Westergren method. |
| Secondary | Change in fecal zonulin | Baseline, month 4, month 8 and month 12 | Fecal zonulin measured by ELISA in a stool sample, as a marker of intestinal permeability. |
| Secondary | Change in thyroid function (TSH, free T4 and free T3) | Baseline, month 4, month 8 and month 12 | Serum TSH, free T4 and free T3 measured by immunoassay. |
| Secondary | Change in micronutrient status (25-hydroxyvitamin D, ferritin and selenium) | Baseline, month 4, month 8 and month 12 | Serum 25-hydroxyvitamin D, ferritin and selenium. |
| Secondary | Change in fatigue (Fatigue Severity Scale) | Monthly from baseline to month 12 | FSS: 9 items scored 1 to 7; total score is the mean of items (range 1-7). Higher scores indicate more fatigue. |
| Secondary | Change in anxiety and depression (Hospital Anxiety and Depression Scale) | Monthly from baseline to month 12 | HADS: 14 items; anxiety and depression subscales each range 0-21. Higher scores indicate worse symptoms. |
| Secondary | Change in health-related quality of life (WHOQOL-BREF) | Monthly from baseline to month 12 | WHOQOL-BREF: 26 items across physical, psychological, social and environmental domains. Higher scores indicate better quality of life. |
1 to 10 of 15Source ClinicalTrials.gov
See all 15 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers4
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07879690
GET https://conductscience.org/api/trials/v1/NCT07879690/registered