Trial · NCT07880197
Knotless Versus Conventional Sutures for Wound Closure in Cerebral Palsy Multilevel Surgery
NCT07880197, Not applicable, Not yet recruiting, University of California, Los Angeles
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Knotless Versus Conventional Sutures for Wound Closure in Cerebral Palsy Multilevel Surgery. Trials, record NCT07880197. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07880197
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Knotless Versus Conventional Sutures for Wound Closure in Cerebral Palsy Multilevel Surgery
- NCT number
- NCT07880197
- Status
- Not yet recruiting
- Phases
- Not applicable
- Enrollment
- 50 participants, estimated
- Lead sponsor
- University of California, Los Angeles
- Conditions
- Cerebral Palsy
- Interventions
- Knotless barbed suture, Conventional suture
- First posted
- 2026-10-19
- Last updated
- 2026-10-19
Source ClinicalTrials.gov
Registered outcomes11
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Wound Closure Time per Incision | Day of surgery (intraoperative) | Total time, in seconds, to close each study incision, measured during surgery by a research assistant with a stopwatch. Timing starts when final irrigation of the wound is complete and the closing suture is handed to the surgeon responsible for closure, and stops when the final suture is cut; the timer is paused for interruptions unrelated to wound closure. Closure time is compared between knotless barbed and conventional closure within matched incision pairs (the same procedure performed on the left and right limbs). |
| Secondary | Incidence of Surgical Site Infection | Up to 6 months after surgery (NHSN windows of 30 and 90 days) | Proportion of study incisions with a surgical site infection, classified as superficial incisional, deep incisional, or organ/space infection using the CDC National Healthcare Safety Network (NHSN) definitions. Superficial infections are counted within 30 days and deep incisional and organ/space infections within 90 days of surgery; wound infections diagnosed later, through the 6-month visit, are also recorded. |
| Secondary | Incidence of Wound Dehiscence | Assessed at 7-10 days, 4-6 weeks, 3 months, and 6 months after surgery | Proportion of study incisions with separation of the wound edges after closure, classified as superficial (skin and subcutaneous tissue) or deep (involving the fascia), with the management required recorded. |
| Secondary | Incidence of Suture Spitting and Other Wound Complications | Assessed at 7-10 days, 4-6 weeks, 3 months, and 6 months after surgery | Proportion of study incisions with suture spitting (extrusion of suture material through the skin or incision) or other wound events: hematoma, seroma, delayed wound healing, suture granuloma, or local hypersensitivity reaction. |
| Secondary | Observer-Rated Scar Appearance (Stony Brook Scar Evaluation Scale) | 4-6 weeks, 3 months, and 6 months after surgery (6 months is the principal time point) | Scar appearance of each study incision scored from standardized photographs by two independent reviewers masked to allocation. The Stony Brook Scar Evaluation Scale rates width, height, color, suture marks, and overall appearance as 0 or 1 each, for a total score from 0 (worst) to 5 (best); the mean of the two reviewers' scores is used. |
| Secondary | Patient-Reported Scar Assessment (POSAS Patient Scale) | 3 and 6 months after surgery (6 months is the principal time point) | Patient- or caregiver-reported assessment of each study incision using the patient scale of the Patient and Observer Scar Assessment Scale (POSAS). Six items (pain, itching, color, stiffness, thickness, and irregularity) are each rated from 1 (like normal skin) to 10 (worst imaginable) and summed to a total from 6 to 60; lower scores indicate a better scar. The overall opinion of the scar is rated separately from 1 to 10. |
| Secondary | Number of Device-Related Events | From surgery through 6 months after surgery | Number of intraoperative device problems (suture breakage, needle detachment, or loss of tissue hold) and postoperative device-related events (suture extrusion, suture granuloma, or hypersensitivity reaction) for each closure method. |
| Secondary | Projected Closure Time Saved per Surgical Case | Day of surgery (intraoperative) | For each participant, the within-pair differences in closure time (conventional minus knotless barbed closure) summed across all matched incision pairs, reported in minutes per case and converted to estimated operating room cost (US dollars) using published per-minute operating room costs. |
| Other | Closure Time per Centimeter of Incision | Day of surgery (intraoperative) | Closure time in seconds divided by incision length in centimeters, with length measured using a sterile ruler immediately before closure; compared between closure methods within matched incision pairs. |
| Other | Closure Time Difference by Surgeon Training Level and Procedure Type | Day of surgery (intraoperative) | Within-pair difference in closure time (seconds) analyzed according to the closing surgeon's level of training (attending surgeon, fellow, or resident) and the type of procedure. |
1 to 10 of 11Source ClinicalTrials.gov
See all 11 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07880197
GET https://conductscience.org/api/trials/v1/NCT07880197/registered