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Trial · NCT07880509

Effectiveness of Pre-Procedural CPC and Zinc Mouthwash in Reducing Dental Aerosols

NCT07880509, Phase 4, Not yet recruiting, Colgate Palmolive

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Effectiveness of Pre-Procedural CPC and Zinc Mouthwash in Reducing Dental Aerosols. Trials, record NCT07880509. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07880509

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Effectiveness of Pre-Procedural CPC and Zinc Mouthwash in Reducing Dental Aerosols
NCT number
NCT07880509
Status
Not yet recruiting
Phases
Phase 4
Enrollment
60 participants, estimated
Lead sponsor
Colgate Palmolive
Conditions
Bacterial Contamination
Interventions
0.09% CPC + Zinc Lactate Mouthwash, 0.2% Chlorhexidine Mouthwash, Water
First posted
2026-10-19
Last updated
2026-10-19

Source ClinicalTrials.gov

Registered outcomes4

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryTotal Viable Bacterial Colony-Forming Units (CFUs) in Dental AerosolsDay 1 (at 10 minutes into prophylaxis and 15 minutes post-prophylaxis)Mean number of total viable bacterial colony-forming units (CFUs) across all blood agar plates and sampling locations combined.
SecondaryAerosol Dispersal Colony-Forming Units (CFUs) by LocationDay 1 (at 10 minutes into prophylaxis and 15 minutes post-prophylaxis)Difference in mean CFU counts across specific aerosol sampling sites: clinician forehead, patient chest, and dental light reflector.
SecondaryChange in Salivary Bacterial LoadBaseline (pre-rinse), immediately post-rinse, and 15 minutes post-prophylaxis on Day 1Mean absolute change and percentage change in salivary bacterial counts (Log CFU/mL) from baseline.
SecondaryProportional Shifts in Oral Microbial SpeciesDay 1 (at 10 minutes into prophylaxis and 15 minutes post-prophylaxis)Proportional shifts in 40 targeted oral bacterial species analyzed via Checkerboard DNA-DNA Hybridization.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07880509

GET https://conductscience.org/api/trials/v1/NCT07880509/registered