Trial · NCT07880704
Cardiovascular Impacts of E-cigarettes Among Older Adults
NCT07880704, Not applicable, Not yet recruiting, University of Maryland, Baltimore
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Cardiovascular Impacts of E-cigarettes Among Older Adults. Trials, record NCT07880704. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07880704
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Cardiovascular Impacts of E-cigarettes Among Older Adults
- NCT number
- NCT07880704
- Status
- Not yet recruiting
- Phases
- Not applicable
- Enrollment
- 40 participants, estimated
- Lead sponsor
- University of Maryland, Baltimore
- Conditions
- Hypertension, Tobacco Cigarette Smoking, Electronic Cigarettes, Cardiovascular
- Interventions
- Nicotine E-cigarette, Tobacco Cigarette
- First posted
- 2026-10-19
- Last updated
- 2026-10-19
Source ClinicalTrials.gov
Registered outcomes6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Heart Rate (laboratory) | Session 1 (baseline), Session 2 after 14 days of product use (smoked cigarettes or e-cigarettes counterbalanced), Session 3 after 14 additional days of product use (smoked cigarettes or e-cigarettes counterbalanced) | Resting heart rate, in beats per minute, will be measured in the research laboratory. Averaged readings will be used. |
| Primary | Blood Pressure (laboratory) | Session 1 (baseline), Session 2 after 14 days of product use (smoked cigarettes or e-cigarettes counterbalanced), Session 3 after 14 additional days of product use (smoked cigarettes or e-cigarettes counterbalanced) | Blood pressure, in mmHg, will be measured in the laboratory (systolic and diastolic). Averaged readings will be used. |
| Primary | Blood Pressure (remote monitoring) | Collected daily during each of two 14-day product-use periods: one involving cigarette smoking and the other involving e-cigarette use. | Averaged at-home blood pressure readings (systolic and diastolic) |
| Primary | Daily Resting Heart Rate (remote monitoring) | Collected continuously across 14 days for each condition (smoking and e-cigarette) | Daily average derived from wrist-worn wearable activity tracker. Calculated by dividing daily average heart rate, measured in beats per minute, by the total daily step count recorded by a study-provided wearable device. |
| Primary | Daily Heart Rate Variability (remote monitoring) | Collected continuously across 14 days for each condition (smoking and e-cigarette) | Daily average derived from wrist-worn wearable activity tracker |
| Primary | Daily Heart Rate per Step | Daily throughout each of two 14-day product-use periods, approximately study Days 1-28. | Daily resting heart rate, in beats per minute, will be obtained using a study-provided wearable device. Repeated daily measurements will be compared within participants between the cigarette-smoking and e-cigarette periods. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants1
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years |
|---|---|---|---|---|---|
| R03HL188068 | Comparative Cardiovascular Effects of Combustible and Electronic Cigarettes in Older Adults with Hypertension | Kleykamp, Bethea AnnaLouise | UNIVERSITY OF MARYLAND BALTIMORE | NATIONAL HEART LUNG AND BLOOD INSTITUTE | 2026 |
Source NIH RePORTER
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07880704
GET https://conductscience.org/api/trials/v1/NCT07880704/registered