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Trial · NCT07880743

Extended Post-Operative Oral Tranexamic Acid Dosing After ACL Reconstruction

NCT07880743, Phase 3, Not yet recruiting, Dave Bernholt

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Extended Post-Operative Oral Tranexamic Acid Dosing After ACL Reconstruction. Trials, record NCT07880743. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07880743

On this page

Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Extended Post-Operative Oral Tranexamic Acid Dosing After ACL Reconstruction
NCT number
NCT07880743
Status
Not yet recruiting
Phases
Phase 3
Enrollment
100 participants, estimated
Lead sponsor
Dave Bernholt
Conditions
Anterior Cruciate Ligament Injuries, Anterior Cruciate Ligament Rupture, Pain, Postoperative
Interventions
Tranexamic Acid, Placebo
First posted
2026-10-19
Last updated
2026-10-26

Source ClinicalTrials.gov

Registered outcomes3

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryPostoperative pain (VAS)2 weeks after surgeryVisual Analog Scale pain score, 0 (no pain) to 10 (worst pain); higher scores mean worse pain.
PrimaryOpioid consumptionDay of surgery through 2 weeks after surgeryTotal morphine milligram equivalents (MME) taken, calculated from home diary pill counts and verified by capsule count.
PrimaryKnee range of motion2 weeks after surgeryKnee flexion and extension in degrees, measured by goniometer by an MD, PA or NP.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers3

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
33630652BACKGROUNDPubMed
34358640BACKGROUNDPubMed
38430972BACKGROUNDPubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07880743

GET https://conductscience.org/api/trials/v1/NCT07880743/registered