Trial · NCT07880964
Role of HFNC During FOB in Patients With Respiratory Failure
NCT07880964, Not applicable, Recruiting, Mansoura University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Role of HFNC During FOB in Patients With Respiratory Failure. Trials, record NCT07880964. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07880964
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Role of HFNC During FOB in Patients With Respiratory Failure
- NCT number
- NCT07880964
- Status
- Recruiting
- Phases
- Not applicable
- Enrollment
- 60 participants, estimated
- Lead sponsor
- Mansoura University
- Conditions
- Respiratory Failure, Respiratory Failure With Hypercapnia
- Interventions
- High flow nasal canula
- First posted
- 2026-10-19
- Last updated
- 2026-10-19
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in PaO₂/FiO₂ ratio: Change in the arterial oxygen partial pressure to inspired oxygen fraction ratio (PaO₂/FiO₂) | From baseline before fiber-optic bronchoscopy to 2 hours after completion of the procedure. | The PaO₂/FiO₂ ratio will be assessed using arterial blood gas analysis to evaluate changes in oxygenation in patients receiving high-flow nasal cannula (HFNC) during fiber-optic bronchoscopy. Arterial blood samples will be collected at baseline before the procedure and 2 hours after its completion while participants are receiving HFNC |
| Primary | Change in PaCO₂: Change in arterial partial pressure of carbon dioxide (PaCO₂) from baseline before fiber-optic bronchoscopy to 2 hours after completion of the procedure. | From baseline before fiber-optic bronchoscopy to 2 hours after completion of the procedure. | PaCO₂ will be measured using arterial blood gas analysis (mmHg) to assess changes in ventilation in patients receiving HFNC during fiber-optic bronchoscopy. Arterial blood samples will be collected at baseline before the procedure and 2 hours after its completion while participants are receiving HFNC |
| Secondary | Incidence of oxygen desaturation during fiber-optic bronchoscopy | From initiation of fiber-optic bronchoscopy until completion of the procedure. | The occurrence of oxygen desaturation, defined as SpO₂ ≤90% lasting more than 10 seconds, during fiber-optic bronchoscopy. The number and duration of desaturation episodes, lowest SpO₂, and time to first desaturation will also be recorded. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 39050533 | RESULT |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07880964
GET https://conductscience.org/api/trials/v1/NCT07880964/registered