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Trial · NCT07881406

Salivary and GCF Biomarkers in Periodontal Health, Gingivitis and Periodontitis

NCT07881406, Not yet recruiting, Yuzuncu Yil University

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Salivary and GCF Biomarkers in Periodontal Health, Gingivitis and Periodontitis. Trials, record NCT07881406. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07881406

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Salivary and GCF Biomarkers in Periodontal Health, Gingivitis and Periodontitis
NCT number
NCT07881406
Status
Not yet recruiting
Enrollment
60 participants, estimated
Lead sponsor
Yuzuncu Yil University
Conditions
Periodontal Health, Gingivitis, Periodontitis
Interventions
Clinical periodontal examination, ELISA-based biomarker analysis
First posted
2026-10-19
Last updated
2026-10-23

Source ClinicalTrials.gov

Registered outcomes5

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryIrisin levels in saliva and GCFSingle time point at baseline (day of sample collection)Salivary and GCF irisin levels measured by human-specific ELISA kit, compared across periodontal health, gingivitis, and periodontitis groups
PrimaryIL-6 levels in saliva and GCFSingle time point at baseline (day of sample collection)Salivary and GCF IL-6 levels measured by human-specific ELISA kit, compared across periodontal health, gingivitis, and periodontitis groups
SecondaryTNF-α levels in saliva and GCFSingle time point at baseline (day of sample collection)Salivary and GCF TNF-α levels measured by human-specific ELISA kit, compared across periodontal health, gingivitis, and periodontitis groups
SecondaryIL-10 levels in saliva and GCFSingle time point at baseline (day of sample collection)Salivary and GCF IL-10 levels measured by human-specific ELISA kit, compared across periodontal health, gingivitis, and periodontitis groups
SecondaryCorrelation between biomarker levels and clinical periodontal parametersSingle time point at baseline (day of sample collection)Association between salivary and GCF biomarker levels (irisin, IL-6, TNF-α, IL-10) and clinical parameters including PD, BOP, and CAL.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers6

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
22126282BACKGROUNDPubMed
26556177BACKGROUNDPubMed
29926944BACKGROUNDPubMed
33998029BACKGROUNDPubMed
35099433BACKGROUNDPubMed
35442384BACKGROUNDPubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07881406

GET https://conductscience.org/api/trials/v1/NCT07881406/registered