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Trial · NCT07881601

Registered outcomes12

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryChange in Flow-Mediated Dilation (FMD)Baseline, Week 4, Week 8Change in Flow-Mediated Dilation (FMD), a measure of vascular endothelial function.
SecondaryChange in Total Plasma CoQ10 ConcentrationBaseline, Week 4, Week 8Change from baseline in the absolute concentration of total coenzyme Q10 (CoQ10) in plasma, measured in μg/mL.
SecondaryChange in Plasma Ubiquinol ConcentrationBaseline, Week 4, Week 8Change from baseline in the absolute concentration of reduced coenzyme Q10 (ubiquinol) in plasma, measured in μg/mL.
SecondaryChange in Plasma Ubiquinone ConcentrationBaseline, Week 4, Week 8Change from baseline in the absolute concentration of oxidized coenzyme Q10 (ubiquinone) in plasma, measured in μg/mL.
SecondaryChange in Ratio of Reduced to Total CoQ10Baseline, Week 4, Week 8Change from baseline in the ratio of reduced CoQ10 (ubiquinol) to total CoQ10 in plasma.
SecondaryChange in Plasma Nitric Oxide (NO)Baseline, Week 4, Week 8Change from baseline in plasma nitric oxide (NO), assessed by nitrite/nitrate quantification.
SecondaryChange in LDL Oxidation SusceptibilityBaseline, Week 4, Week 8Change from baseline in LDL oxidation susceptibility, measured as lag time using a copper-induced assay.
SecondaryChange in Malondialdehyde (MDA) LevelsBaseline, Week 4, Week 8Change from baseline in serum levels of malondialdehyde (MDA), an oxidative stress marker.
SecondaryChange in Oxidized LDL (oxLDL) LevelsBaseline, Week 4, Week 8Change from baseline in serum levels of oxidized low-density lipoprotein (oxLDL), an oxidative stress marker.
SecondaryChange in Total Antioxidant Capacity (TAC)Baseline, Week 4, Week 8Change from baseline in serum total antioxidant capacity (TAC).
OtherTreatment-Emergent Adverse EventsBaseline, Week 4, Week 8Number and proportion of Treatment-Emergent Adverse Events (TEAEs).
OtherTreatment-Emergent Serious Adverse EventsBaseline, Week 4, Week 8Number and proportion of Treatment-Emergent Serious Adverse Events (TESAEs).

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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