Trial · NCT07882030
Early Administration of Angong Niuhuang Pill for Disabling Acute Ischemic Stroke (EAGER Trial)
NCT07882030, Not applicable, Not yet recruiting, Xuanwu Hospital, Beijing
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Early Administration of Angong Niuhuang Pill for Disabling Acute Ischemic Stroke (EAGER Trial). Trials, record NCT07882030. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07882030
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Early Administration of Angong Niuhuang Pill for Disabling Acute Ischemic Stroke (EAGER Trial)
- NCT number
- NCT07882030
- Status
- Not yet recruiting
- Phases
- Not applicable
- Enrollment
- 1,200 participants, estimated
- Lead sponsor
- Xuanwu Hospital, Beijing
- Conditions
- Acute Ischemic Stroke
- Interventions
- Angong Niuhuang Pill, Angong Niuhuang Pill Matching Placebo
- First posted
- 2026-10-20
- Last updated
- 2026-10-20
Source ClinicalTrials.gov
Registered outcomes13
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Functional Independence at 90 Days | 90 ± 7 days after randomization | The proportion of participants achieving functional independence at 90 days after randomization, defined as a modified Rankin Scale (mRS) score of 0 to 2. The mRS ranges from 0 to 6, with higher scores indicating greater disability. |
| Secondary | Excellent Functional Outcome at 90 Days | 90 ± 7 days after randomization | The proportion of participants achieving an excellent functional outcome at 90 days after randomization, defined as a modified Rankin Scale (mRS) score of 0 to 1. |
| Secondary | Distribution of Modified Rankin Scale Scores at 90 Days | 90 ± 7 days after randomization | The distribution of modified Rankin Scale (mRS) scores from 0 to 6 at 90 days after randomization. Higher scores indicate greater disability. |
| Secondary | Change in Barthel Index From Baseline to Day 90 | Baseline to 90 ± 7 days after randomization | The change in Barthel Index score from baseline to 90 days after randomization. |
| Secondary | Change in NIHSS Score From Baseline to Day 14 | Baseline to day 14 ± 3 after randomization | The change in National Institutes of Health Stroke Scale (NIHSS) score from baseline to day 14 after randomization. The NIHSS ranges from 0 to 42, with higher scores indicating greater neurological impairment. |
| Secondary | Neurological Improvement at Day 14 | Day 14 ± 3 after randomization | The proportion of participants with neurological improvement at day 14 after randomization, defined as a reduction in NIHSS score of at least 4 points from baseline. |
| Secondary | Change in NIHSS Score From Baseline to Day 7 | Baseline to day 7 after randomization | The change in National Institutes of Health Stroke Scale (NIHSS) score from baseline to day 7 after randomization.The total NIHSS score ranges from 0 to 42, where higher scores represent greater neurological impairment (worse outcome). A decrease in score indicates improvement. |
| Secondary | Symptomatic Intracranial Hemorrhage Within 7 Days | Within 7 days after randomization | The proportion of participants experiencing symptomatic intracranial hemorrhage within 7 days after randomization, defined according to the European Cooperative Acute Stroke Study III (ECASS III) criteria. |
| Other | Serious Adverse Events Within 90 Days | From randomization through day 90 ± 7 | The proportion of participants experiencing at least one serious adverse event from randomization through day 90. |
| Other | All-Cause Mortality Within 90 Days | Within 90 ± 7 days after randomization | The proportion of participants who die from any cause within 90 days after randomization. |
1 to 10 of 13Source ClinicalTrials.gov
See all 13 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 39501831 | BACKGROUND |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07882030
GET https://conductscience.org/api/trials/v1/NCT07882030/registered