Trial · NCT07883265
Comparison of HPI-guided Norepinephrine Boluses, ClearSight-guided Norepinephrine Infusion, and Oscillometric-guided Norepinephrine Infusion for Blood Pressure Stability During Cesarean Delivery
NCT07883265, Not applicable, Not yet recruiting, National Taiwan University Hospital
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Comparison of HPI-guided Norepinephrine Boluses, ClearSight-guided Norepinephrine Infusion, and Oscillometric-guided Norepinephrine Infusion for Blood Pressure Stability During Cesarean Delivery. Trials, record NCT07883265. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07883265
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Comparison of HPI-guided Norepinephrine Boluses, ClearSight-guided Norepinephrine Infusion, and Oscillometric-guided Norepinephrine Infusion for Blood Pressure Stability During Cesarean Delivery
- NCT number
- NCT07883265
- Status
- Not yet recruiting
- Phases
- Not applicable
- Enrollment
- 180 participants, estimated
- Lead sponsor
- National Taiwan University Hospital
- Conditions
- Hypotension During Cesarean Delivery, Blood Pressure Monitoring
- Interventions
Hypotension Prediction Index derived from the noninvasive arterial waveform, Continuous noninvasive arterial pressure monitoring (HPI blinded), Norepinephrine intermittent bolus, intermittent oscillometric blood pressure monitoring (standard care)
- First posted
- 2026-10-20
- Last updated
- 2026-10-20
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Time-weighted average of hypotension (TWA MAP < 65 mmHg) | From completion of spinal anesthesia to 30 minutes after spinal anesthesia. | Time-weighted average of mean arterial pressure below 65 mmHg, calculated as the area under the 65 mmHg threshold (depth of hypotension in mmHg × duration in minutes) divided by total duration of the observation period, derived from ClearSight continuous arterial pressure data. Unit: mmHg. |
| Secondary | Umbilical cord blood gas pH value | Immediately after delivery of the neonate (within 5 minutes of cord clamping) | Umbilical arterial and venous pH measured from paired cord blood samples collected from the clamped placental segment immediately after delivery. |
| Secondary | Time-adjusted area under the curve for systolic blood pressure below 80% of baseline | From completion of spinal anesthesia to 30 minutes after spinal anesthesia. | Area between the measured systolic blood pressure and the threshold of 0.8 × baseline systolic blood pressure, divided by observation time, derived from ClearSight data. Unit: mmHg. |
| Secondary | Incidence of hypotension | From completion of spinal anesthesia to end of surgery. | Proportion of participants with at least one hypotensive event, defined as ClearSight MAP \< 65 mmHg lasting more than 1 minute. |
| Secondary | Total duration of hypotension | From completion of spinal anesthesia to end of surgery. | Cumulative time (minutes) with ClearSight MAP \< 65 mmHg. |
| Secondary | Area under the threshold of MAP < 65 mmHg | From completion of spinal anesthesia to end of surgery. | Cumulative area under the 65 mmHg threshold (mmHg × min) derived from ClearSight MAP data. |
| Secondary | Total norepinephrine dose | From completion of spinal anesthesia to end of surgery. | Cumulative dose of norepinephrine administered (bolus plus infusion), in mcg. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 41693355 | RESULT |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07883265
GET https://conductscience.org/api/trials/v1/NCT07883265/registered