Trial · NCT07883421
Immunogenicity of Standard-Dose Versus High-Dose Influenza Vaccines in Older Adults in Singapore
NCT07883421, Phase 4, Not yet recruiting, Tan Tock Seng Hospital
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Immunogenicity of Standard-Dose Versus High-Dose Influenza Vaccines in Older Adults in Singapore. Trials, record NCT07883421. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07883421
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Immunogenicity of Standard-Dose Versus High-Dose Influenza Vaccines in Older Adults in Singapore
- NCT number
- NCT07883421
- Status
- Not yet recruiting
- Phases
- Phase 4
- Enrollment
- 150 participants, estimated
- Lead sponsor
- Tan Tock Seng Hospital
- Conditions
- Influenza
- Interventions
- High-dose influenza vaccine, Standard-dose influenza vaccine
- First posted
- 2026-10-20
- Last updated
- 2026-10-20
Source ClinicalTrials.gov
Registered outcomes14
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | GMT ratio (HD-IIV/SD-IIV) for A/H3N2 strain in the vaccine | Day 14 | |
| Secondary | GMT ratio (HD-IIV/SD-IIV) for A/H3N2 strain in the vaccine | Day 180 and 330 | |
| Secondary | GMT ratio (HD-IIV/SD-IIV) for A/H1N1 strain in the vaccine | Day 14, 180 and 330 | |
| Secondary | GMT ratio (HD-IIV/SD-IIV) for B/Victoria strain in the vaccine | Day 14, 180 and 330 | |
| Secondary | HI GMTs against influenza vaccine strains | Day 14, 180 and 330 | |
| Secondary | Geometric mean ratio (GMR) of HI titres post- versus pre-vaccination against vaccine strains | Day 14 to 330 | |
| Secondary | Seroprotection rates against vaccine strains | Day 14 to 330 | Seroprotection is defined as HI titre ≥1:40 |
| Secondary | Seroconversion rates against vaccines strains | Day 14 to 330 | Seroconversion is defined as a pre-vaccination (Day 0) HI titre \<10 and post-vaccination HI titre ≥40 or at least a 4-fold increase in HI titres from a pre-vaccination HI titre ≥10. |
| Secondary | Micro-neutralization titres against vaccine strains | Day 14, 180 and 330 | |
| Secondary | Frequency of solicited local (injection site) and systemic adverse events | 3 days post-vaccination |
1 to 10 of 14Source ClinicalTrials.gov
See all 14 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers3
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07883421
GET https://conductscience.org/api/trials/v1/NCT07883421/registered