Trial · NCT07883486
Post-operative Pain and Apical Healing After Root Canal (re)Treatment With Laser-activated Irrigation Versus Sonic or no Activation
NCT07883486, Not applicable, Recruiting, University Ghent
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Post-operative Pain and Apical Healing After Root Canal (re)Treatment With Laser-activated Irrigation Versus Sonic or no Activation. Trials, record NCT07883486. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07883486
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Post-operative Pain and Apical Healing After Root Canal (re)Treatment With Laser-activated Irrigation Versus Sonic or no Activation
- NCT number
- NCT07883486
- Status
- Recruiting
- Phases
- Not applicable
- Enrollment
- 183 participants, estimated
- Lead sponsor
- University Ghent
- Conditions
- Apical Periodontitis, Post Operative Pain, Acute
- Interventions
- sonically activated irrigation, laser activated irrigation, conventional needle irrigation
- First posted
- 2026-10-20
- Last updated
- 2026-11-10
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | post-operative pain | Post-operative pain is scored immediately after the treatment and 6 hours, 24 hours, 48 hours, 72 hours and 96 hours after treatment. | The post-operative pain immediately after completion of treatment is scored on the Visual Analogue Scale (VAS), with a score between 0 (no pain) and 10 (worst pain imaginable). Patients are asked to fill out a pain diary 6 hours, 24 hours, 48 hours, 72 hours and 96 hours after treatment with a pain score on the VAS. |
| Primary | tooth survival | up to 2 years post-treatment | presence of the treated tooth inside the mouth |
| Primary | apical healing | up to 2 years post-treatment | The pre-operative and recall periapical radiographs are compared for the periapical index (PAI). On the radiographs, the apical periodontitis lesion is outlined and the surface of the lesion is calculated using software. The surface of the apical periodontitis lesion on the follow-up radiograph is compared to the pre-operative radiograph. Teeth are categorized into the following three outcome categories based on analysing the change in the PAI: * Strict radiographic success (healed teeth): absence of clinical signs or symptoms, and PAI-score of 1 or 2 at follow-up. * Loose radiographic success (healing teeth): absence of clinical signs or symptoms, and a lower PAI-score (or smaller surface of the lesion) compared to the pre-operative radiograph. * Failure (non-healing): clinical signs or symptoms (including pain, swelling, sinus tract), or asymptomatic with an unchanged PAI-score (or surface of the lesion), or increase in PAI-score (or surface of the lesion) at follow-up. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07883486
GET https://conductscience.org/api/trials/v1/NCT07883486/registered