Trial · NCT07883655
Advanced Multi-omics and -System Approaches to Identify Novel Biomarkers for SMA
NCT07883655, Recruiting, Istituto Giannina Gaslini
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Advanced Multi-omics and -System Approaches to Identify Novel Biomarkers for SMA. Trials, record NCT07883655. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07883655
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Advanced Multi-omics and -System Approaches to Identify Novel Biomarkers for SMA
- NCT number
- NCT07883655
- Status
- Recruiting
- Enrollment
- 200 participants, estimated
- Lead sponsor
- Istituto Giannina Gaslini
- Conditions
- Spinal Muscular Atrophy (SMA)
- First posted
- 2026-10-20
- Last updated
- 2026-10-20
Source ClinicalTrials.gov
Registered outcomes6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Identification of biomarkers that distinguish patients with SMA from healthy controls and differentiate between disease phenotypes (p < 0.05). | through study completion, an average of 2 years | |
| Primary | Functional validation of biomarkers in SMA organoids and their association with treatment response | through study completion, an average of 2 years | |
| Primary | Identification of biomarkers predictive of clinical disease progression in newborns with SMA (accuracy >80%) | through study completion, an average of 2 years | |
| Secondary | Integrated molecular signatures predictive of treatment response (accuracy >80%). | through study completion, an average of 2 years | |
| Secondary | Identification of ≥3 biomarkers conserved in C. elegans models and associated with phenotypic effects. | through study completion, an average of 2 years | |
| Secondary | Development of a prognostic algorithm based on biomarker levels at neonatal diagnosis (sensitivity/specificity >80%). | through study completion, an average of 2 years |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07883655
GET https://conductscience.org/api/trials/v1/NCT07883655/registered