Trial · NCT07883993
Comparing AI and Standard Pregnancy Chatbots
NCT07883993, Not applicable, Not yet recruiting, Nivi, Inc.
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Comparing AI and Standard Pregnancy Chatbots. Trials, record NCT07883993. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07883993
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Comparing AI and Standard Pregnancy Chatbots
- NCT number
- NCT07883993
- Status
- Not yet recruiting
- Phases
- Not applicable
- Enrollment
- 2,500 participants, estimated
- Lead sponsor
- Nivi, Inc.
- Conditions
- Pregnancy, Prenatal Care, Maternal Health
- Interventions
- Scripted maternal health chatbot, MATRI retrieval-augmented maternal health chatbot
- First posted
- 2026-10-20
- Last updated
- 2026-10-20
Source ClinicalTrials.gov
Registered outcomes12
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Percentage of weeks with any user interaction | Weekly from enrollment through delivery or gestational week 41, up to 31 weeks | Binary measure of whether the user gave any response during the specified week. Measured from platform interaction logs. |
| Primary | Mean conversational turns per week | Weekly from enrollment through delivery or gestational week 41, up to 31 weeks | Number of user-initiated messages sent to the chatbot in a given week, averaged across the participant's follow-up weeks. Measured from platform interaction logs. |
| Primary | Mean number of substantive user queries per week | Weekly from enrollment through delivery or gestational week 41, up to 31 weeks | Number of substantive queries sent by the participant in a given week, averaged across her follow-up weeks. A substantive query is a user-initiated free-text message, excluding greetings, acknowledgments, single-word replies, emoji-only messages, system strings, and blanks. The same classification procedure is applied in both arms. Measured from platform interaction logs. |
| Primary | Percentage of weeks with any substantive user query | Weekly from enrollment through delivery or gestational week 41, up to 31 weeks | Binary measure of whether a participant gave any substantive query during the given week, defined as above. Measured from platform interaction logs. |
| Secondary | Percentage of weeks with user response to weekly template message | Weekly from enrollment through delivery or gestational week 41, up to 31 weeks | Binary measure of whether the user responded to the template message of the specified week |
| Secondary | Discernment index from user responses to clinical scenarios | Baseline and gestational weeks 38 to 41, up to 31 weeks | Score from 0 to 2 across a paired scenario battery. Each participant sees one high-severity and one low-severity scenario at baseline and the other pair at endline, so no scenario is answered twice. Each scenario scores 1 for the keyed action and 0 otherwise. High-severity and low-severity accuracy are also reported separately. |
| Secondary | Self-reported prenatal care attendance and health-seeking behaviors | From enrollment through delivery or gestational week 41, up to 31 weeks | Total antenatal care visits during the pregnancy, self-reported by the participant. Visits since enrollment are reported at midline and total visits for the pregnancy at endline. |
| Secondary | Self-reported acute care-seeking | Every 6 to 8 weeks from enrollment through delivery or gestational week 41, up to 31 weeks | The share of reported worrying symptoms for which the participant sought care the same day. Collected through between-survey pulse checks and the midline questionnaire. |
| Secondary | Usability of the chatbot, adapted System Usability Scale | Gestational weeks 28 to 30, up to 20 weeks after enrollment | Mean score across a 5-item usability instrument adapted from the System Usability Scale, with items rated from 1 (strongly disagree) to 5 (strongly agree). Possible range 1 to 5. Higher scores indicate better perceived usability. Negatively worded items are reverse-scored before averaging. |
| Secondary | Net Promoter Score | Gestational weeks 38 to 41 or within one week of delivery, up to 31 weeks | Single survey item asking how likely the participant is to recommend the chatbot to a pregnant friend or family member, rated from 0 (not at all likely) to 10 (extremely likely). Higher scores indicate greater likelihood to recommend. |
1 to 10 of 12Source ClinicalTrials.gov
See all 12 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07883993
GET https://conductscience.org/api/trials/v1/NCT07883993/registered