Trial · NCT07884747
Hypernatremia Fluid Therapy in Childhood Diarrhoea
NCT07884747, Not applicable, Enrolling by invitation, International Centre for Diarrhoeal Disease Research, Bangladesh
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Hypernatremia Fluid Therapy in Childhood Diarrhoea. Trials, record NCT07884747. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07884747
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Hypernatremia Fluid Therapy in Childhood Diarrhoea
- NCT number
- NCT07884747
- Status
- Enrolling by invitation
- Phases
- Not applicable
- Enrollment
- 268 participants, estimated
- Lead sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
- Conditions
- Hypernatremia, Acute Watery Diarrhea
- Interventions
- Oral rehydration solution (ORS)
- First posted
- 2026-10-21
- Last updated
- 2026-10-21
Source ClinicalTrials.gov
Registered outcomes6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | All-cause mortality from initiation of the intervention until hospital discharge among children under five years of age with hypernatremic dehydration associated with diarrhoea. | From enrollment to discharge (approximately 7 days) | Events of death any time during hospitalization after initiation of intervention until discharge. |
| Secondary | Incidence of rapid serum-sodium (>12 mmol/L in 24 hours) | From enrollment to the normalization of sodium level (Approximately 3 days from enrollment) | Serum sodium will be measured at 0 hours, 6 hours and then 24 hourly and there after until normalization of sodium. |
| Secondary | Need for ancillary interventions (e.g., 3% NaCl, anticonvulsants) | From enrollment to discharge (approximately 7 days) | Incidence of convulsions and use of anti-convulsant and 3% NaCl during the rehydration period |
| Secondary | Acute kidney injury (AKI) events | From enrollment to the normalization of both sodium and creatinine level (Approximately 3 days from enrollment) | Serum creatinine level at 0 hours, 6 hours, every 24 hour then there after until normalization of creatinine |
| Secondary | Poor neurological outcome at month 1 and month 6 | After treatment complete to end of follow up at month 6 | Neurodevelopmental outcomes (cerebral oedema, developmental delay) at discharge (Approximately at Day7) from hospital and during follow-up visits at month 1, month 6 |
| Secondary | The case fatality at 6-month follow-up | After discharge o end of follow up at month 6 | Events of death any time after discharge from hospitalization to complete of 6 month follow up period |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers12
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07884747
GET https://conductscience.org/api/trials/v1/NCT07884747/registered