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Trial · NCT07884903

Registered outcomes11

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryIncidence of Type 2 Diabetes Mellitus3 years3-year incidence of new-onset type 2 diabetes mellitus diagnosed according to ADA criteria (fasting glucose ≥7.0 mmol/L, HbA1c ≥6.5%, or 2h OGTT ≥11.1 mmol/L)
PrimaryIncidence of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)3 years3-year incidence of new-onset MASLD diagnosed by abdominal ultrasound and/or FibroScan with hepatic steatosis, excluding other causes of liver disease
PrimaryIncidence of Hypertension3 years3-year incidence of new-onset hypertension (systolic BP ≥140 mmHg and/or diastolic BP ≥90 mmHg on at least 2 occasions, or initiation of antihypertensive medication)
PrimaryIncidence of Atherosclerotic Cardiovascular Disease (ASCVD)3 years3-year incidence of ASCVD events including coronary heart disease, cerebral infarction, transient ischemic attack (TIA), and peripheral artery disease, confirmed by clinical diagnosis and imaging
SecondaryIncidence of Obstructive Sleep Apnea-Hypopnea Syndrome (OSAHS)3 yearsDiagnosed by polysomnography with AHI ≥5 events/hour
SecondaryIncidence of Polycystic Ovary Syndrome (PCOS)3 yearsDiagnosed by Rotterdam criteria in women of reproductive age
SecondaryIncidence of Osteoarticular Disease3 yearsNew-onset lumbar/knee/hip joint disease confirmed by imaging
SecondaryIncidence of Hyperuricemia3 yearsSerum uric acid \>420 μmol/L (men) or \>360 μmol/L (women)
SecondaryIncidence of Dyslipidemia3 yearsNew-onset abnormal lipid profile requiring treatment per guidelines
SecondaryIncidence of Microalbuminuria3 yearsUrine albumin-to-creatinine ratio ≥30 mg/g on 2 occasions
SecondaryProgression of Prediabetes to Diabetes3 yearsConversion from prediabetes (IFG/IGT) to overt type 2 diabetes

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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