Trial · NCT07885059
Dose-sparing Balanced Propofol Sedation in Colonoscopy
NCT07885059, Not applicable, Completed, University of Split, School of Medicine
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Dose-sparing Balanced Propofol Sedation in Colonoscopy. Trials, record NCT07885059. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07885059
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Dose-sparing Balanced Propofol Sedation in Colonoscopy
- NCT number
- NCT07885059
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 76 participants, actual
- Lead sponsor
- University of Split, School of Medicine
- Conditions
- Colonoscopy, Sedation and Analgesia
- Interventions
- Standard-dose balanced propofol analgosedation, Dose-sparing balanced propofol analgosedation
- First posted
- 2026-10-21
- Last updated
- 2026-10-21
Source ClinicalTrials.gov
Registered outcomes19
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Patient satisfaction | At completion of post-procedural recovery on the day of colonoscopy. | Patient satisfaction was assessed using a study-specific four-item questionnaire. Two items assessed satisfaction with the colonoscopy procedure and satisfaction with analgosedation using separate 11-point numerical rating scales ranging from 0 (completely dissatisfied) to 10 (extremely satisfied). Two additional binary items assessed whether the participant would recommend the same approach to relatives or friends and whether the participant would agree to undergo colonoscopy using the same approach again. |
| Primary | Incidence of clinically relevant respiratory adverse events | From administration of sedation through completion of monitored post-procedural recovery on the day of colonoscopy. | Incidence of protocol-defined respiratory adverse events, reported by event type. Respiratory events included apnea lasting more than 30 seconds, oxygen saturation below 90%, respiratory rate below 10 or above 20 breaths per minute, end-tidal CO2 below 35 mmHg, and the need for airway-opening interventions. Apnea lasting more than 30 seconds was analyzed as the principal respiratory safety endpoint. |
| Secondary | Total propofol dose | From initial propofol administration until completion of the colonoscopy. | Total cumulative dose of propofol administered during the colonoscopy, expressed in milligrams. |
| Secondary | Number of additional propofol boluses | From initial propofol administration until completion of the colonoscopy. | Number of additional propofol boluses administered after the initial protocol-defined propofol dose. |
| Secondary | Cumulative additional propofol dose | From initial propofol administration until completion of the colonoscopy. | Total cumulative dose of additional propofol administered after the initial protocol-defined propofol dose, expressed in milligrams. |
| Secondary | Early recovery time | From completion of colonoscopy through the early post-procedural recovery period on the day of the procedure. | Time from completion of the colonoscopy until achievement of the predefined early post-anaesthesia recovery criterion based on the Modified Aldrete Score. |
| Secondary | Total recovery time | From completion of colonoscopy until completion of monitored post-procedural recovery on the day of the procedure. | Time from completion of the colonoscopy until achievement of predefined discharge-readiness criteria based on post-anaesthesia recovery assessment, including the Post-Anesthesia Discharge Scoring System (PADSS). |
| Secondary | Cecal intubation rate | During colonoscopy. | Proportion of colonoscopies in which the colonoscope was successfully advanced to the cecum. |
| Secondary | Cecal intubation time | During the index colonoscopy. | Time from insertion of the colonoscope until successful intubation of the cecum. |
| Secondary | Colonoscope withdrawal time | During colonoscopy. | Time from initiation of colonoscope withdrawal from the cecum until completion of the examination. |
1 to 10 of 19Source ClinicalTrials.gov
See all 19 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07885059
GET https://conductscience.org/api/trials/v1/NCT07885059/registered