Trial · NCT07885124
Driving Pressure-Guided Individualized PEEP Versus Standard PEEP: Effects on Postoperative Pulmonary Complications in Upper Abdominal Digestive Surgery
NCT07885124, Not applicable, Recruiting, Hopital Charles Nicolle
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Driving Pressure-Guided Individualized PEEP Versus Standard PEEP: Effects on Postoperative Pulmonary Complications in Upper Abdominal Digestive Surgery. Trials, record NCT07885124. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07885124
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Driving Pressure-Guided Individualized PEEP Versus Standard PEEP: Effects on Postoperative Pulmonary Complications in Upper Abdominal Digestive Surgery
- NCT number
- NCT07885124
- Status
- Recruiting
- Phases
- Not applicable
- Enrollment
- 210 participants, estimated
- Lead sponsor
- Hopital Charles Nicolle
- Conditions
- Postoperative Pulmonary Complications, Mechanical Ventilation
- Interventions
- Driving Pressure-Guided Individualized PEEP, Standard PEEP
- First posted
- 2026-10-21
- Last updated
- 2026-10-21
Source ClinicalTrials.gov
Registered outcomes15
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | postoperative pulmonary complications | From the end of surgery through postoperative day 7 (up to 7 days) | Incidence of postoperative pulmonary complications occurring within the first 7 postoperative days, according to the study-defined criteria. |
| Secondary | Length of hospital stay | From the day of surgery through hospital discharge, assessed up to 30 days after surgery. | Length of hospital stay will be calculated as the number of days from the date of surgery to the date of hospital discharge. |
| Secondary | Postoperative Intensive Care Unit Admission | From the end of surgery through hospital discharge, assessed up to 30 days after surgery. | Number and percentage of participants requiring admission to an intensive care unit after surgery. |
| Secondary | Intensive Care Unit Length of Stay | At intensive care unit discharge, assessed up to 30 days after surgery. | Among participants admitted to the intensive care unit, length of stay measured in calendar days from intensive care unit admission to intensive care unit discharge. |
| Secondary | Intraoperative Tidal Volume | 10 minutes after tracheal intubation; 1, 2, and 3 hours after intubation; and at the end of surgery. | Tidal volume delivered during mechanical ventilation, expressed in mL/kg of ideal body weight and recorded at predefined intraoperative time points. |
| Secondary | Median Intraoperative Positive End-Expiratory Pressure | 10 minutes after tracheal intubation; 1, 2, and 3 hours after intubation; and at the end of surgery. | Median positive end-expiratory pressure (PEEP) applied during intraoperative mechanical ventilation, expressed in cmH2O and calculated from values recorded at the predefined intraoperative assessment points. |
| Secondary | Intraoperative Peak Airway Pressure | 10 minutes after tracheal intubation; 1, 2, and 3 hours after intubation; and at the end of surgery. | Peak airway pressure measured during intraoperative mechanical ventilation, expressed in cmH2O. |
| Secondary | Intraoperative Plateau Pressure | From initiation of mechanical ventilation after tracheal intubation through the end of surgery | Plateau pressure measured during an end-inspiratory occlusion lasting 2 to 3 seconds, expressed in cmH2O. |
| Secondary | Intraoperative Static Respiratory System Compliance | From initiation of mechanical ventilation after tracheal intubation through the end of surgery | Static respiratory system compliance calculated as tidal volume divided by the difference between plateau pressure and positive end-expiratory pressure, expressed in mL/cmH2O. |
| Secondary | Intraoperative Dynamic Respiratory System Compliance | From initiation of mechanical ventilation after tracheal intubation through the end of surgery | Dynamic respiratory system compliance calculated as tidal volume divided by the difference between peak airway pressure and positive end-expiratory pressure, expressed in mL/cmH2O. |
1 to 10 of 15Source ClinicalTrials.gov
See all 15 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 24894577 | BACKGROUND |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07885124
GET https://conductscience.org/api/trials/v1/NCT07885124/registered