Trial · NCT07885241
Telerehabilitation-Supported Exercise in Women With Lipedema
NCT07885241, Not applicable, Not yet recruiting, Istanbul University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Telerehabilitation-Supported Exercise in Women With Lipedema. Trials, record NCT07885241. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07885241
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Telerehabilitation-Supported Exercise in Women With Lipedema
- NCT number
- NCT07885241
- Status
- Not yet recruiting
- Phases
- Not applicable
- Enrollment
- 66 participants, estimated
- Lead sponsor
- Istanbul University
- Conditions
- Lipedema
- Interventions
- Telerehabilitation-Supported Exercise, Home Exercise Program
- First posted
- 2026-10-21
- Last updated
- 2026-10-27
Source ClinicalTrials.gov
Registered outcomes10
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Pain Intensity Assessed by Visual Analog Scale (VAS) | Baseline, week 12, week 24 | Pain severity in the affected extremities will be assessed using a 10-cm Visual Analog Scale. The scale ranges from "no pain" to "the most severe pain imaginable." Participants will be asked to mark the point on the line that best represents the severity of their pain. The distance from the beginning of the scale to the marked point will be measured and recorded as the pain score. Higher scores indicate greater pain severity. |
| Secondary | Six-Minute Walk Test | Baseline and Week 12, week 24 | Walking capacity and exercise tolerance will be assessed using the 6-Minute Walk Test in a 30-meter corridor. Participants will be instructed to walk as many laps as possible during 6 minutes. At the beginning of each minute, the assessor will remind the participant of the remaining time and provide standardized verbal encouragement. The total distance walked at the end of 6 minutes will be recorded in meters. A greater walking distance indicates better functional exercise capacity. |
| Secondary | Lower Extremity Function Assessed by Lower Extremity Functional Scale (LEFS) | Baseline and Week 12, week 24 | Functional capacity during activities of daily living will be assessed using the 20-item Lower Extremity Functional Scale. Each item is scored from 0 to 4: 0 indicates inability to perform the activity or extreme difficulty, 1 indicates quite a bit of difficulty, 2 indicates moderate difficulty, 3 indicates a little difficulty, and 4 indicates no difficulty. The total score ranges from 0 to 80, with higher scores indicating better lower extremity functional capacity. |
| Secondary | Lipedema-Related Symptoms | Baseline and Week 12, week 24 | The severity of 12 lipedema-related symptoms will be assessed using 10-cm Visual Analog Scales. The evaluated symptoms include pain, tenderness to touch and pressure, swelling, fullness or tightness, heaviness, excessive sensations of heat or cold, easy bruising, fatigue, difficulty walking, reduced quality of life, and dissatisfaction with leg appearance. Each scale ranges from "no symptom" to "the most severe symptom." Higher scores indicate greater symptom severity. |
| Secondary | Pressure Pain Threshold Assessed by Algometry | Baseline and Week 12, week 24 | Pressure pain threshold will be assessed using a digital algometer. Before measurement, the anterior thigh, pretibial region, lateral aspect of the leg, and medial supramalleolar region of both lower extremities will be marked. The algometer will be applied perpendicular to each measurement point. Participants will indicate when pressure is first perceived as painful, and the value displayed on the device will be recorded as the pressure pain threshold. Measurements will be repeated three times at each point at 5-second intervals, and the mean value will be calculated. |
| Secondary | Lower Extremity Volume Assessed by Circumference Measurements | Baseline and Week 12, week 24 | Bilateral leg circumference measurements will be obtained while participants are in the supine position. Measurements will begin at the level of the lateral malleolus and continue proximally at 4-cm intervals up to 56 cm. All measurements will be recorded in centimeters. The obtained circumference measurements will be used to calculate total lower extremity and thigh volume according to the principles of the Kuhnke disc method. Percentage changes in volume will be calculated at follow-up assessments. |
| Secondary | Quality of Life Assessed by Short Form-36 (SF-36) | Baseline and Week 12, week 24 | Quality of life will be assessed using the Short Form-36 Health Survey. The scale consists of eight domains: physical functioning, role limitations due to physical health, bodily pain, general health perceptions, vitality, social functioning, role limitations due to emotional problems, and mental health. Each domain is scored from 0 to 100, with higher scores indicating better health-related quality of life. Physical and mental health component scores will also be evaluated. |
| Secondary | Subcutaneous Tissue Thickness Assessed by Ultrasonography | Baseline and Week 12, week 24 | Subcutaneous tissue thickness will be measured using a MYLAB Esaote 60 ultrasound device with a 7-13 MHz linear transducer while participants are in the supine position. Measurements will be obtained bilaterally from predefined reference areas at the anterior thigh, pretibial region, lateral aspect of the leg, and medial supramalleolar region. The transducer will be positioned perpendicular to the dermal-subcutaneous junction. Three measurements will be obtained from each region, and the mean value will be recorded. |
| Secondary | 30-Second Sit-to-Stand Test | Baseline and Week 12, week 24 | Lower extremity muscle strength and functional endurance will be assessed using the 30-Second Chair Stand Test. Participants will be instructed to repeatedly stand up from and sit down on a chair with back support while keeping their arms crossed over their chest. The number of correctly completed repetitions within 30 seconds will be recorded. A higher number of repetitions indicates better lower extremity strength and functional endurance. |
| Secondary | Timed Up and Go Test | Baseline, Week 12. week 24 | Mobility and balance will be assessed using the Timed Up and Go Test. Participants will be instructed to stand up from a chair, walk 3 meters, turn around, walk back to the chair, and sit down. The time required to complete the task will be measured and recorded in seconds. A shorter completion time indicates better functional mobility and balance. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07885241
GET https://conductscience.org/api/trials/v1/NCT07885241/registered