Trial · NCT07885514
Exercise, Mediterranean Diet and Inflammation in Heart Failure
NCT07885514, Not applicable, Not yet recruiting, Hospital Severo Ochoa
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Exercise, Mediterranean Diet and Inflammation in Heart Failure. Trials, record NCT07885514. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07885514
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Exercise, Mediterranean Diet and Inflammation in Heart Failure
- NCT number
- NCT07885514
- Status
- Not yet recruiting
- Phases
- Not applicable
- Enrollment
- 214 participants, estimated
- Lead sponsor
- Hospital Severo Ochoa
- Conditions
- Heart Failure, Heart Failure Preserved Ejection Fraction, Heart Failure, Diastolic (HFpEF), Chronic Inflammation
- Interventions
- Structured exercise training program, Mediterranean diet counseling, Standard heart failure management
- First posted
- 2026-10-21
- Last updated
- 2026-10-21
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Hierarchical composite of cardiovascular death, recurrent heart failure hospitalizations, 6-minute walk test distance, and quality of life (KCCQ) at 12 months | 12 months | Hierarchical win ratio composite endpoint, ranked in descending order of clinical importance: 1) cardiovascular death; 2) recurrent HF hospitalizations (time to first and repeated events); 3) change from baseline in 6-minute walk test distance; 4) change from baseline in KCCQ score. Events adjudicated by a blinded independent Clinical Events Adjudication Committee. Comparison between arms by win ratio; analyzed by intention to treat. |
| Secondary | All-cause mortality | 12 months | Time to all-cause death compared between arms. |
| Secondary | All-cause hospitalization | 12 months | Time to all-cause hospitalization compared between arms. |
| Secondary | Change in diastolic function (echocardiography) | Baseline, 6 months, 12 months | Change from baseline in echocardiographic parameters of diastolic function at 6 and 12 months. |
| Secondary | Change in HF biomarkers | Baseline, 6 months, 12 months | Change from baseline in NT-proBNP and CA125 serum levels. |
| Other | Adherence to exercise and dietary interventions | 12 months | Degree of adherence of participants in the intervention arm to the exercise program and the Mediterranean diet plan, and its impact on the primary endpoint. |
| Other | Predictive value of the INFLA score | 12 months | Value of the INFLA score to predict the composite of cardiovascular death and HF decompensation. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers8
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07885514
GET https://conductscience.org/api/trials/v1/NCT07885514/registered