Trial · NCT07885657
Prophylactic Norepinephrine for Prevention of Acute Kidney Injury in Living-Donor Liver Transplantation
NCT07885657, Not applicable, Not yet recruiting, Mansoura University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Prophylactic Norepinephrine for Prevention of Acute Kidney Injury in Living-Donor Liver Transplantation. Trials, record NCT07885657. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07885657
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Prophylactic Norepinephrine for Prevention of Acute Kidney Injury in Living-Donor Liver Transplantation
- NCT number
- NCT07885657
- Status
- Not yet recruiting
- Phases
- Not applicable
- Enrollment
- 84 participants, estimated
- Lead sponsor
- Mansoura University
- Conditions
- Noradrenaline
- Interventions
Norepinephrine started prophylactically immediately post induction of general anesthesia, Norepinephrine infusion will only initiated if mean arterial pressure <65 mmHg despite preload optimization (stroke volume variation <12%) or if systemic vascular resistance <800 dynes•s/cm⁵
- First posted
- 2026-10-21
- Last updated
- 2026-10-21
Source ClinicalTrials.gov
Registered outcomes8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Incidence of postoperative acute kidney injury defined according to the Kidney Disease Improving Global Outcome (KDIGO) criteria | within the first 7 days postoperatively | Incidence |
| Secondary | Post-operative renal perfusion Assessed by renal resistive index (RRI) measured by ultrasound (US) | at 24 then at 72 hours Post-operatively | index |
| Secondary | Incidence of any norepinephrine specific side effects | within intraoperative period | Incidence |
| Secondary | Total intraoperative fluid volume administered (crystalloids, colloids and blood products) | intraopeatively | milliliter |
| Secondary | Diuretics use and their doses (Furosemide will be administered when clinically indicated for volume overload or persistent oliguria after adequate intravascular volume status has been established) | intraoperatively and 7 days postoperatively | mg |
| Secondary | Incidence and duration of intraoperative hypotension (mean arterial pressure less than 65) | intraoperatively | Incidence |
| Secondary | Serial changes in estimated glomerular filtration rate (eGFR) calculated by the creatinine-based equation at baseline | postoperative at day 1, 3, 7, 30, and 90 | mL/min/1.73 m² |
| Secondary | Fibrinogen/Albumin Ratio calculation | at 24 then at 72 hours Post-operatively | mg/dL |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07885657
GET https://conductscience.org/api/trials/v1/NCT07885657/registered