Trial · NCT07885683
MagSense® Human Epidermal Growth Factor Receptor 2 (HER2) Imaging Agent (MSH2IA)
NCT07885683, Phase 1, Phase 2, Not yet recruiting, Imagion Biosystems, Inc.
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. MagSense® Human Epidermal Growth Factor Receptor 2 (HER2) Imaging Agent (MSH2IA). Trials, record NCT07885683. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07885683
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- MagSense® Human Epidermal Growth Factor Receptor 2 (HER2) Imaging Agent (MSH2IA)
- NCT number
- NCT07885683
- Status
- Not yet recruiting
- Phases
- Phase 1, Phase 2
- Enrollment
- 70 participants, estimated
- Lead sponsor
- Imagion Biosystems, Inc.
- Conditions
- HER2-positive Breast Cancer
- Interventions
- The MagSense® HER2 Imaging Agent (MSH2IA)
- First posted
- 2026-10-21
- Last updated
- 2026-10-21
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Phase 1b: Level of Fe in blood | 24 hours post injection | PK MSH2IA Fe concentration \> LLOQ in human whole blood |
| Primary | Phase 2 (Imaging Schedule): Dose and Imaging schedule for MSH2IA | 24 hours post injection | MSH2IA dose to image suspicious versus normal nodes and Post dose MRI imaging timing |
| Primary | Phase 2 (Diagnostic Performance): Diagnostic performance comparison between MSH2IA and SOC | 24 hours post injection | Patient level concordance of MSH2IA imaging to clinical pathology and Patient level concordance of MSH2IA to AxUS as measured by PPV, NPV, and Overall Predictive Concordance (PPV+NPV). |
| Secondary | Safety and Tolerability of MSH2IA Across All Phases | From baseline through 1 year | All Phases: Assess safety and tolerability of MSH2IA Incidence and severity of AEs, serious adverse events and Injection site reactions (ISRs) |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers12
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07885683
GET https://conductscience.org/api/trials/v1/NCT07885683/registered