Trial · NCT07885826
Prospective Longitudinal Study of Sleep, Brain Activity, and Plasma Analyses in Patients Undergoing Epilepsy Surgery
NCT07885826, Not yet recruiting, Region Skane
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Prospective Longitudinal Study of Sleep, Brain Activity, and Plasma Analyses in Patients Undergoing Epilepsy Surgery. Trials, record NCT07885826. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07885826
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Prospective Longitudinal Study of Sleep, Brain Activity, and Plasma Analyses in Patients Undergoing Epilepsy Surgery
- NCT number
- NCT07885826
- Status
- Not yet recruiting
- Enrollment
- 40 participants, estimated
- Lead sponsor
- Region Skane
- Conditions
- Epilepsy, Sleep, Drug Resistant Epilepsy, Epilepsy Sleep, Surgery
- First posted
- 2026-10-21
- Last updated
- 2026-10-21
Source ClinicalTrials.gov
Registered outcomes19
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in Polysomnography-Derived Sleep Efficiency | Baseline (before surgery), approximately 2 months after surgery, and approximately 6 months after surgery | Sleep efficiency measured by polysomnography (PSG), calculated as total sleep time divided by time in bed, expressed as a percentage (%). Changes from baseline to approximately 2 and 6 months after epilepsy surgery will be assessed. |
| Primary | Change in Polysomnography-Derived Total Sleep Time | Baseline (before surgery), approximately 2 months after surgery, and approximately 6 months after surgery | Total sleep time measured by polysomnography (PSG), expressed in minutes. Changes from baseline to approximately 2 and 6 months after epilepsy surgery will be assessed. |
| Primary | Change in Polysomnography-Derived Sleep Stage Distribution | Baseline (before surgery), approximately 2 months after surgery, and approximately 6 months after surgery | Percentage of total sleep time spent in each sleep stage (N1, N2, N3 and REM), measured by polysomnography (PSG). Changes in each sleep stage percentage from baseline to approximately 2 and 6 months after epilepsy surgery will be assessed. |
| Primary | Change in Polysomnography-Derived Wake After Sleep Onset | Baseline (before surgery), approximately 2 months after surgery, and approximately 6 months after surgery | Wake after sleep onset (WASO), measured by polysomnography (PSG) and expressed in minutes, will be used as a measure of sleep fragmentation. Changes from baseline to approximately 2 and 6 months after epilepsy surgery will be assessed. |
| Primary | Change in Polysomnography-Derived Arousal Index | Baseline (before surgery), approximately 2 months after surgery, and approximately 6 months after surgery. | Arousal index measured by polysomnography (PSG), defined as the number of EEG arousals per hour of total sleep time (arousals/hour), scored according to standard sleep scoring criteria. |
| Primary | Change in Actigraphy-Derived Total Sleep Time | Baseline (before surgery), approximately 2 months after surgery, and approximately 6 months after surgery | Mean nightly total sleep time measured by wrist actigraphy over a 14-day recording period, expressed in minutes per night. Changes from baseline to approximately 2 and 6 months after epilepsy surgery will be assessed. |
| Primary | Change in Actigraphy-Derived Sleep Efficiency | Baseline (before surgery), approximately 2 months after surgery, and approximately 6 months after surgery | Mean nightly sleep efficiency measured by wrist actigraphy over a 14-day recording period, calculated as total sleep time divided by time in bed and expressed as a percentage (%). Changes from baseline to approximately 2 and 6 months after epilepsy surgery will be assessed. |
| Primary | Change in Actigraphy-Derived Sleep Timing Variability | Baseline (before surgery), approximately 2 months after surgery, and approximately 6 months after surgery | Night-to-night variability in sleep onset time, quantified as the standard deviation of sleep onset times across the 14-day wrist actigraphy recording period and expressed in minutes. Changes from baseline to approximately 2 and 6 months after epilepsy surgery will be assessed. |
| Primary | Correlation Between PSG-Derived Sleep Efficiency and Weekly Seizure Frequency | Baseline (before surgery), approximately 2 months after surgery, and approximately 6 months after surgery | Correlation between sleep efficiency measured by polysomnography (PSG), expressed as a percentage (%), and weekly epileptic seizure frequency, expressed as number of seizures per week and collected through weekly patient reports. |
| Primary | Change in Pittsburgh Sleep Quality Index (PSQI) Global Score | Baseline (before surgery), approximately 2 months after surgery, and approximately 6 months after surgery | Subjective sleep quality will be assessed using the Pittsburgh Sleep Quality Index (PSQI). The global score ranges from 0 to 21, with higher scores indicating poorer sleep quality. Changes from baseline to approximately 2 and 6 months after epilepsy surgery will be assessed. |
1 to 10 of 19Source ClinicalTrials.gov
See all 19 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07885826
GET https://conductscience.org/api/trials/v1/NCT07885826/registered