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Trial · NCT07886372

Effects of Mango on Insulin Sensitivity in Prediabetes

NCT07886372, Not applicable, Not yet recruiting, Clinical Nutrition Research Center, Illinois Institute of Technology

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Effects of Mango on Insulin Sensitivity in Prediabetes. Trials, record NCT07886372. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07886372

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Effects of Mango on Insulin Sensitivity in Prediabetes
NCT number
NCT07886372
Status
Not yet recruiting
Phases
Not applicable
Enrollment
64 participants, estimated
Lead sponsor
Clinical Nutrition Research Center, Illinois Institute of Technology
Conditions
Pre Diabetes
Interventions
Mango juice, Control Beverage
First posted
2026-10-21
Last updated
2026-10-29

Source ClinicalTrials.gov

Registered outcomes8

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryFasting Plasma Glucose ConcentrationBaseline and Week 6Fasting plasma glucose concentration will be measured in plasma samples using a Randox automated clinical analyzer.
PrimaryFasting Plasma Insulin ConcentrationBaseline and Week 6Fasting plasma insulin concentration will be measured in plasma samples using a Randox automated clinical analyzer.
PrimaryInsulin SensitivityBaseline and Week 6The Matsuda index for insulin sensitivity will be calculated using validated equations based on paired glucose and insulin values obtained during the Liquid Meal Tolerance Test (LMTT).
SecondaryPlasma Glutathione Peroxidase ActivityBaseline and Week 6Plasma glutathione peroxidase activity will be measured to assess systemic antioxidant enzyme activity before and after the intervention.
SecondaryPlasma Superoxide Dismutase ActivityBaseline and Week 6Plasma superoxide dismutase activity will be measured to assess systemic antioxidant enzyme activity before and after the intervention.
SecondaryExpression of Nrf-2 Pathway GenesBaseline and Week 6
Relative expression of target genes (Nrf-2, glutathione peroxidase 2 \[GLx2\], glutathione S-transferase \[GST\], and NAD(P)H:quinone oxidoreductase-1 \[NQO1\]) will be quantified from blood collected in Paxgene tubes using qPCR.
SecondaryContinuous Glucose Monitoring (CGM)7-day monitoring periods at baseline and Week 6Interstitial glucose profiles will be captured using a continuous glucose monitor worn for 7-days before the LMTT.
SecondaryFasting Plasma Triglyceride ConcentrationBaseline and Week 6Fasting plasma triglyceride concentration will be measured in plasma samples using a Randox automated clinical analyzer.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07886372

GET https://conductscience.org/api/trials/v1/NCT07886372/registered