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Trial · NCT07886593

Diode Laser Added to Non-Surgical Treatment for Peri-Implant Mucositis

NCT07886593, Not applicable, Completed, Universidad Europea de Valencia

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Diode Laser Added to Non-Surgical Treatment for Peri-Implant Mucositis. Trials, record NCT07886593. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07886593

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Diode Laser Added to Non-Surgical Treatment for Peri-Implant Mucositis
NCT number
NCT07886593
Status
Completed
Phases
Not applicable
Enrollment
206 participants, actual
Lead sponsor
Universidad Europea de Valencia
Conditions
Peri-implant Mucositis
Interventions
Conventional Non-Surgical Treatment, Adjunctive Diode Laser Therapy
First posted
2026-10-21
Last updated
2026-10-21

Source ClinicalTrials.gov

Registered outcomes5

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryChange From Baseline in Bleeding on Probing (BOP)Baseline, 4-6 weeks, 3 months, 6 months, and 12 months
leeding on probing was assessed at six peri-implant sites using the modified peri-implant bleeding index described by Mombelli. Scores ranged from 0 to 3, with higher scores indicating greater bleeding severity. Changes from baseline were calculated for each follow-up visit relative to the baseline value.
SecondaryChange From Baseline in Plaque Index (PI)Baseline, 4-6 weeks, 3 months, 6 months, and 12 months
Plaque index was assessed at six peri-implant sites according to the Silness and Löe criteria. Scores ranged from 0 to 3, with higher scores indicating greater plaque accumulation. Changes from baseline were evaluated at each follow-up visit.
SecondaryChange From Baseline in Probing Depth (PD)Baseline, 4-6 weeks, 3 months, 6 months, and 12 months
Probing depth was measured in millimeters at six peri-implant sites using a periodontal probe with an approximate probing force of 0.25 N. Probing depth was defined as the distance from the peri-implant mucosal margin to the base of the peri-implant sulcus. Changes from baseline were evaluated at each follow-up visit.
SecondaryChange From Baseline in Peri-Implant Crevicular Fluid (PICF) VolumeBaseline and 4-6 weeks
Peri-implant crevicular fluid volume was measured using Periopaper strips and quantified with a Periotron 8010 device. Device readings were converted to fluid volume using a previously established calibration curve. Change from baseline was assessed after treatment.
SecondaryChange From Baseline in Matrix Metalloproteinase-8 (MMP-8) LevelsBaseline and 4-6 weeks
MMP-8 concentration in peri-implant crevicular fluid was determined using a commercially available human MMP-8 ELISA kit. Concentrations were calculated from the assay standard curve and expressed as ng/mL. Change from baseline was assessed after treatment.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers2

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
31976039BACKGROUNDPubMed
33282139BACKGROUNDPubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07886593

GET https://conductscience.org/api/trials/v1/NCT07886593/registered