Trial · NCT07887074
Essential Oil Mouthwash - Oral Hygiene
NCT07887074, Not applicable, Completed, China Medical University, Taiwan
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Essential Oil Mouthwash - Oral Hygiene. Trials, record NCT07887074. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07887074
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Essential Oil Mouthwash - Oral Hygiene
- NCT number
- NCT07887074
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 150 participants, actual
- Lead sponsor
- China Medical University, Taiwan
- Conditions
- Oral Hygiene, Oral Health, Dental Plaque, Respiratory Tract Infections (RTI)
- Interventions
- Essential oil mouthwash, Chlorhexidine gluconate alcohol-free mouthwash, Povidone-iodine alcohol-free mouthwash
- First posted
- 2026-10-21
- Last updated
- 2026-10-21
Source ClinicalTrials.gov
Registered outcomes9
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in Oral Health Assessment Tool (OHAT) Score | Baseline (Day 1) and Day 21 | Overall oral health status assessed by a trained assessor blinded to group allocation using the Oral Health Assessment Tool, which comprises eight domains (lips, tongue, gums and oral tissues, saliva, natural teeth, dentures, oral cleanliness, and dental pain), each scored 0-2. Total score ranges from 0 to 16; higher scores indicate poorer oral health. |
| Primary | Change in Plaque Index Score | Baseline (Day 1) and Day 21 | Dental plaque accumulation assessed using a plaque-disclosing agent and scored by a trained assessor blinded to group allocation according to the Silness and Löe criteria: 0 = no plaque, 1 = thin film of plaque along the gingival margin, 2 = visible plaque accumulation, 3 = abundant plaque accumulation. Higher scores indicate greater plaque accumulation. |
| Primary | Change in Halitosis Consequences Inventory (ICH) Score | Baseline (Day 1) and Day 21 | Halitosis-related quality of life assessed using the 18-item self-report Halitosis Consequences Inventory, with each item rated dichotomously for the presence (1) or absence (0) of the corresponding behavioral, emotional, or social consequence of bad breath. Total score ranges from 0 to 18; higher scores indicate greater perceived impact of halitosis. |
| Secondary | Change in Stomatitis Index Score | Baseline (Day 1) and Day 21 | Oral mucosal inflammation assessed by non-invasive visual inspection by a trained assessor blinded to group allocation, using Newton's classification: 0 = no lesions, 1 = localized erythema or pinpoint hyperemia, 2 = diffuse erythema or generalized inflammation, 3 = granular or hyperplastic surface consistent with inflammatory papillary hyperplasia. Higher scores indicate more severe inflammation. |
| Secondary | Change in Self-Perceived Oral Health Status | Baseline (Day 1) and Day 21 | Self-perceived oral health assessed using a single item asking participants to rate their current oral health as good (0), average (1), bad (2), or very bad (3). Higher scores indicate poorer self-perceived oral health. |
| Secondary | Change in Geriatric Oral Health Assessment Index (GOHAI) Score | Baseline (Day 1) and Day 21 | Oral health-related quality of life assessed using the 12-item self-report GOHAI, covering physical function, psychosocial function, and pain or discomfort related to oral health. Each item is rated on a five-point frequency scale (0-4), and the total score is the sum of the 12 items (range 0-48). |
| Secondary | Incidence of Upper Respiratory Tract Symptoms | Baseline (Day 1) and Day 21 | Presence of self-reported upper respiratory tract symptoms (nasal congestion, rhinorrhea, sneezing, or cough), recorded as present or absent and summarized as the number and percentage of participants with any symptom in each group. |
| Secondary | Change in Salivary Oral Microbiota Composition | Baseline (Day 1) and Day 21 | Unstimulated saliva samples collected to characterize oral microbial composition and diversity using \[sequencing method, e.g., 16S rRNA gene sequencing\], including relative abundance of bacterial taxa and alpha- and beta-diversity indices. |
| Secondary | Change in Salivary Inflammatory Markers | Baseline (Day 1) and Day 21 | Concentrations of salivary inflammatory markers \[specify markers, e.g., IL-1β, IL-6, TNF-α\] measured in saliva samples using \[assay method, e.g., enzyme-linked immunosorbent assay\]. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07887074
GET https://conductscience.org/api/trials/v1/NCT07887074/registered