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Trial · NCT07887399

New Treatment in Melasma

NCT07887399, Not applicable, Not yet recruiting, Sohag University

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. New Treatment in Melasma. Trials, record NCT07887399. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07887399

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
New Treatment in Melasma
NCT number
NCT07887399
Status
Not yet recruiting
Phases
Not applicable
Enrollment
75 participants, estimated
Lead sponsor
Sohag University
Conditions
Female, With, Facial, Melasma
Interventions
Tranexamic Acid - topical, Microneedling with Topical Tranexamic acid, Modified Kligman's Formula
First posted
2026-10-21
Last updated
2026-10-21

Source ClinicalTrials.gov

Registered outcomes4

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryChange in Melasma Area and Severity Index (MASI) score from baseline to the end of the treatment period4 months after initiation of treatmentThe mean change in MASI score from baseline to the end of the treatment period (4 months) will be compared among the three treatment groups.
SecondaryPercentage change in Melasma Area and Severity Index (MASI) from baseline to the end of treatment4 months after initiation of treatmentThe percentage change in MASI score from Baseline to the end of the treatment period will be calculated for each participant and compared among the three treatment groups.
SecondaryPatient Satisfaction assessed using a 4-point patient satisfaction scale4 months after initiation of treatment
Patient satisfaction with treatment results will be assessed at the end of the treatment period using a 4-point scale: excellent(\>75% improvement), good(51-75% improvement), fair (26-50% improvement), and poor (0-25% improvement).
SecondaryIncidence of treatment-related adverse eventsfrom initiation of treatment to the end of the treatment period(4months)Treatment safety will be assessed by recording the incidence and types of adverse events, including erythema, irritation, burning, dryness and post-inflammatory hyperpigmentation

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07887399

GET https://conductscience.org/api/trials/v1/NCT07887399/registered