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Trial · NCT07888400

IC ECG Combined With Ultrasound Bubble Test for PICC Tip Positioning Among Oncology Adults: A Three Arm Randomized Controlled Trial

NCT07888400, Not applicable, Completed, Sun Yat-sen University

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. IC ECG Combined With Ultrasound Bubble Test for PICC Tip Positioning Among Oncology Adults: A Three Arm Randomized Controlled Trial. Trials, record NCT07888400. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07888400

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
IC ECG Combined With Ultrasound Bubble Test for PICC Tip Positioning Among Oncology Adults: A Three Arm Randomized Controlled Trial
NCT number
NCT07888400
Status
Completed
Phases
Not applicable
Enrollment
267 participants, actual
Lead sponsor
Sun Yat-sen University
Conditions
PICC Line Placement, Tip Location
Interventions
Combined IC-ECG and Ultrasound PICC Tip Location Technique, IC-ECG PICC Tip Location Technique, Ultrasound PICC Tip Location Technique
First posted
2026-10-22
Last updated
2026-10-22

Source ClinicalTrials.gov

Registered outcomes5

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryOptimal PICC tip placement rateAt the completion of the PICC insertion procedure.
The proportion of participants whose PICC tip is successfully placed at the optimal position (defined as the lower third of the superior vena cava or the cavoatrial junction), confirmed by chest X-ray (CXR).
SecondaryNumber of catheter repositioning attemptsDuring the PICC insertion procedure.The number of times the catheter was withdrawn and readvanced after malposition (e.g., tip in the internal jugular vein, azygos vein, or right atrium) was confirmed.
SecondaryNumber of localisation proceduresDuring the PICC insertion procedure.
The number of independent tip-localisation manoeuvres (e.g., IC-ECG recordings or ultrasound scans) performed to confirm the tip position, excluding instances where the catheter was physically repositioned.
SecondaryLocalisation timeDuring the PICC insertion procedure.The time from the initiation of tip localisation (i.e., when the catheter reached the estimated insertion length) to the final confirmation of the tip position.
SecondaryPush-to-bubbles durationDuring the PICC insertion procedure.The duration from the start of agitated saline injection to the visualization of microbubbles in the right atrium, as assessed by transthoracic echocardiography.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers15

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
19829102RESULTPubMed
25157945RESULTPubMed
28765996RESULTPubMed
30919741RESULTPubMed
32490507RESULTPubMed
32578489RESULTPubMed
33538338RESULTPubMed
34936891RESULTPubMed
35633065RESULTPubMed
35902974RESULTPubMed

1 to 10 of 15

See all 15 papers

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT07888400

GET https://conductscience.org/api/trials/v1/NCT07888400/registered