Trial · NCT07888452
Cooling Eyedrops for Dry Eye
NCT07888452, Phase 4, Not yet recruiting, University of California, Berkeley
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Cooling Eyedrops for Dry Eye. Trials, record NCT07888452. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT07888452
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Cooling Eyedrops for Dry Eye
- NCT number
- NCT07888452
- Status
- Not yet recruiting
- Phases
- Phase 4
- Enrollment
- 50 participants, estimated
- Lead sponsor
- University of California, Berkeley
- Conditions
- Dry Eye
- Interventions
- TRYPTYR Eye Drops, Purilens Plus Non-Preserved Saline Eye Drops
- First posted
- 2026-10-22
- Last updated
- 2026-10-26
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Tear lipid layer thickness (nm) | 10 minutes, 1 hour, and 2 hours after eye drop instillation | Post-eye drop instillation, the LipiView interferometer will be used to measure the thickness of the tear lipid layer on both eyes. |
| Primary | Tear thinning rate (%/sec) | 10 minutes, 1 hour, and 2 hours after eye drop instillation | Post-eye drop instillation, the EasyTear VIEW+ tearscope will be used to measure the rate of tear aqueous thinning on both eyes. |
| Secondary | Ocular Sensation Survey | 10 minutes, 1 hour, and 2 hours after eye drop instillation | Post-eye drop instillation, subjects will be administered a two-item questionnaire about how their eyes feel. The first item asks "Do your eyes feel different after using the eye drop?", Likert scale answers are \[Much Better, A Little Better, No Change, A Little Worse, Much Worse\]. The second item asks respondents to circle all that apply from a list of sensations, \[Soothing, Comfortable, Pleasant, Cooling, Tingling, Burning, Stinging, Irritation, Discomfort, Wet, Tearing, Other: (please specify)\]. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT07888452
GET https://conductscience.org/api/trials/v1/NCT07888452/registered